Devices and methods to treat vascular dissections

Abstract

A device system and method for the treatment of aortic dissections comprising placing a stent in the true lumen and displacing the blood in the false lumen with an inflatable bag.

1 .- 38 . (canceled) 
     
     
         39 . A device system for treating aortic dissections having a false lumen, comprising:
 a support structure for deployment in a true lumen of an aorta; and   an inflatable structure for deployment in the false lumen of the aorta;   wherein:
 the support structure is supported in a compressed state when the device is in a pre-deployment state and during delivery to the true lumen; 
 the support structure is expanded in the aorta when deployed to approximately the diameter of a true lumen of the aorta; 
 the inflatable structure is supported in a compressed state when the device is in a pre-deployment state and during advancement of the inflatable structure into the false lumen; and 
 the inflatable structure is inflated in the false lumen to displace the blood in the false lumen when deployed. 
   
     
     
         40 . A device system of  claim 39 , wherein the support structure is a balloon expandable stent or a self-expanding stent. 
     
     
         41 . The device system of  claim 39 , wherein the support structure is partially covered with a graft to at least substantially seal an entry point of the dissection. 
     
     
         42 . The device system of  claim 39 , wherein a flap of the dissection is sandwiched between the support structure and the inflatable structure after the support structure and the inflatable structure have been deployed. 
     
     
         43 . The device system of  claim 39 , wherein the stent is sized to extend along the entire length of the dissection. 
     
     
         44 . The device system of  claim 39 , wherein the pressure in the inflatable structure is equal to or higher than the aortic blood pressure after the inflatable structure has been inflated in the false lumen to displace the blood in the false lumen. 
     
     
         45 . The device system of  claim 39 , further comprising an inflation medium for inflating the inflatable structure comprising blood. 
     
     
         46 . The device system of claim  30 , further comprising an inflation medium for inflating the inflatable structure comprising a polymer or monomer that crosslinks after injection. 
     
     
         47 . The device system of  claim 46 , wherein the polymer comprises polyethylene glycol. 
     
     
         48 . The device system of  claim 39 , further comprising an inflation medium for inflating the inflatable structure comprising a contrast agent. 
     
     
         49 . The device system of  claim 39 , further comprising an inflation medium for inflating the inflatable structure comprising a hydrogel. 
     
     
         50 . The device system of  claim 39 , wherein the inflatable structure comprises an embolization agent. 
     
     
         51 . The device system of  claim 39 , wherein a wall of the inflatable structure is permeable to blood. 
     
     
         52 . The device system of  claim 39 , wherein a wall of the inflatable structure is impermeable to an inflation medium during a filling phase. 
     
     
         53 . The device system of  claim 39 , wherein the inflatable structure is made from ePTFE, polyurethane, Dacron, woven or knitted biocompatible fibers, or other thin-wall biocompatible material. 
     
     
         54 . The device system of  claim 39 , wherein an inflation medium is injected into the inflatable structure through a detachable fill tube. 
     
     
         55 . The device system of  claim 39 , further comprising a delivery catheter supporting the support structure and the inflatable structure in the pre-deployment state. 
     
     
         56 . A device system for treating aortic dissections having a false lumen, comprising:
 a support structure for positioning in a true lumen of the aorta to support the true lumen when the support structure is deployed; and   an inflatable structure for positioning in the false lumen;   wherein:
 the support structure is supported in a compressed state when the device is in a pre-deployment state and during delivery to the true lumen and expandable in the aorta to the approximate diameter of the true lumen; and 
 the inflatable structure is supported in a compressed state when the device is in a pre-deployment state and during advancement into the false lumen and inflatable in the false lumen to displace the blood in the false lumen. 
   
     
     
         57 .- 73 . (canceled)