US2016296608A1PendingUtilityA1

Treatment methods using atoxic neurotoxin derivatives

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Assignee: VAZQUEZ-CINTRON EDWIN JPriority: Jan 28, 2013Filed: Apr 15, 2016Published: Oct 13, 2016
Est. expiryJan 28, 2033(~6.5 yrs left)· nominal 20-yr term from priority
Inventors:Edwin J. Vazquez-CintronKonstantin IchtchenkoPhilip A. Band
A61P 25/04A61P 27/02A61P 25/02A61P 25/06A61P 25/08A61P 29/00A61P 17/16A61P 1/00A61P 21/02A61P 13/10A61P 19/02A61P 13/02A61P 17/00A61P 1/04A61P 25/00C12Y 304/24069C12N 9/52A61K 9/0019C07K 14/33A61K 38/4893C07K 2319/50C07K 14/001Y02A50/30
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Claims

Abstract

The present invention relates to a treatment method. This method involves contacting a subject with an isolated, physiologically active, atoxic derivative of a Clostridial neurotoxin. Contacting is carried out to treat the subject. The derivative of a Clostridial neurotoxin does not possess a cargo attachment peptide sequence at its N-terminus.

Claims

exact text as granted — not AI-modified
What is claimed: 
     
         1 . A treatment method comprising:
 contacting a subject with an isolated, physiologically active, atoxic derivative of a Clostridial neurotoxin, said contacting being carried out to treat the subject, with the proviso that the derivative of a Clostridial neurotoxin does not possess a cargo attachment peptide sequence at its N-terminus.

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