Chinese herb medicine composition in the form of jelly

Abstract

A Chinese herbal medical composition in the form of jelly, wherein a Chinese herbal medicine is contained in a base containing at least one substance selected from the group consisting of carrageenan, carob bean gum and xanthan gum and not containing phosphate buffer. The Chinese herbal medical composition hardy muses syneresis, is superior in the preservative stability, is broadly applicable to a Chinese herbal medicine and is orally taken without taking care of the bitter of a Chinese herbal medicine.

What is claimed is: 
     
         1 . A Chinese herbal medical composition in the form of jelly, consisting of a Chinese herbal medicine in a base,
 wherein the Chinese herbal medicine is selected from the group consisting of Hachimi-jio-gan, Keishi-bukuryo-gan, and Seijo-bofu-to, and is present in an amount less than 60 w/w % per total amount of the composition,   wherein the base consists of 0.01 to 10.0 w/w % carrageenan, 0.01 to 10.0 w/w % carob bean gum, 0.01 to 10.0 w/w % xanthan gum, per total amount of the composition, and at least one pharmaceutically acceptable additive selected from the group consisting of a stabilizing agent, a corrective agent, an emulsifying agent, a dispersion agent, a sweetening agent, a flavoring agent, a coloring agent, and a preservative,   wherein the carrageenan is iota carrageenan or kappa carrageenan, or a mixture thereof and   wherein the base does not include a phosphate buffer or agar.   
     
     
         2 . The Chinese herbal medical composition according to  claim 1 ,
 wherein the Chinese herbal medicine is present in an amount less than 50 w/w % per total amount of the composition, and   wherein the base consists of 0.05 to 5.0 w/w % carrageenan, 0.05 to 5.0 w/w % carob bean gum, and 0.05 to 5.0 w/w % xanthan gum, per total amount of the composition, and at least one pharmaceutically acceptable additive selected from the group consisting of a stabilizing agent, a corrective agent, an emulsifying agent, a dispersion agent, a sweetening agent, a flavoring agent, a coloring agent, and a preservative.   
     
     
         3 . The Chinese herbal medical composition according to  claim 1 ,
 wherein the Chinese herbal medicine is present in an amount less than 30 w/w % per total amount of the composition, and   wherein the base consists of 0.08 to 2.0 w/w % carrageenan, 0.1 to 2.0 w/w % carob bean gum, and 0.08 to 2.0 w/w % xanthan gum, per total amount of the composition, and at least one pharmaceutically acceptable additive selected from the group consisting of a stabilizing agent, a corrective agent, an emulsifying agent, a dispersion agent, a sweetening agent, a flavoring agent, a coloring agent, and a preservative.   
     
     
         4 . The Chinese herbal medical composition according to  claim 1 , wherein the amount of the Chinese herbal medicine is 14 w/w % or more per total amount of the composition. 
     
     
         5 . The Chinese herbal medical composition according to  claim 1 ,
 wherein the Chinese herbal medicine is Hachimi-jio-gan, and is present in an amount of 14 w/w % per total amount of the composition.   
     
     
         6 . The Chinese herbal medical composition according to  claim 5 ,
 wherein the base consists of 1 w/w % carrageenan, 0.2 w/w % carob bean gum, and 0.4 w/w % xanthan gum, per total amount of the composition, and at least one pharmaceutically acceptable additive selected from the group consisting of a stabilizing agent, a corrective agent, an emulsifying agent, a dispersion agent, a sweetening agent, a flavoring agent, a coloring agent, and a preservative.   
     
     
         7 . The Chinese herbal medical composition according to  claim 6 ,
 wherein the at least one pharmaceutically acceptable additive present in the base are 6 w/w % hydrogenated maltose starch syrup, 6 w/w % D-sorbitol, 6 w/w % glycerin, 1 w/w % propylene glycol, 0.02 w/w % propyl parahydroxybenzoate, and 65.38 w/w % water, per total amount of the composition.   
     
     
         8 . The Chinese herbal medical composition according to  claim 1 ,
 wherein the Chinese herbal medicine is Keishi-bukuryo-gan, and is present in an amount of 14 w/w % per total amount of the composition.   
     
     
         9 . The Chinese herbal medical composition according to  claim 8 ,
 wherein the base consists of 1 w/w % carrageenan, 0.25 w/w % carob bean gum, and 0.45 w/w % xanthan gum, per total amount of the composition, and at least one pharmaceutically acceptable additive selected from the group consisting of a stabilizing agent, a corrective agent, an emulsifying agent, a dispersion agent, a sweetening agent, a flavoring agent, a coloring agent, and a preservative.   
     
     
         10 . The Chinese herbal medical composition according to  claim 9 ,
 wherein the at least one pharmaceutically acceptable additive present in the base are 6 w/w % hydrogenated maltose starch syrup, 6 w/w % D-sorbitol, 6 w/w % glycerin, 1 w/w % propylene glycol, 0.02 w/w % propyl parahydroxybenzoate, and 65.28 w/w % water, per total amount of the composition.   
     
     
         11 . The Chinese herbal medical composition according to  claim 8 ,
 wherein the base consists of 1.1 w/w % carrageenan, 0.25 w/w % carob bean gum, and 0.45 w/w % xanthan gum, per total amount of the composition, and at least one pharmaceutically acceptable additive selected from the group consisting of a stabilizing agent, a corrective agent, an emulsifying agent, a dispersion agent, a sweetening agent, a flavoring agent, a coloring agent, and a preservative.   
     
     
         12 . The Chinese herbal medical composition according to  claim 11 ,
 wherein the at least one pharmaceutically acceptable additive present in the base are 6 w/w % hydrogenated maltose starch syrup, 6 w/w % D-sorbitol, 6 w/w % glycerin, 1 w/w % propylene glycol, 0.02 w/w % propyl parahydroxybenzoate, and 65.18 w/w % water, per total amount of the composition.   
     
     
         13 . The Chinese herbal medical composition according to  claim 1  wherein the Chinese herbal medicine is Seijo-bofu-to, and is present in an amount of 14 w/w % per total amount of the composition. 
     
     
         14 . The Chinese herbal medical composition according to  claim 13 ,
 wherein the base consists of 1 w/w % carrageenan, 0.2 w/w % carob bean gum, and 0.4 w/w % xanthan gum, per total amount of the composition, and at least one pharmaceutically acceptable additive selected from the group consisting of a stabilizing agent, a corrective agent, an emulsifying agent, a dispersion agent, a sweetening agent, a flavoring agent, a coloring agent, and a preservative.   
     
     
         15 . The Chinese herbal medical composition according to  claim 14 ,
 wherein the at least one pharmaceutically acceptable additive present in the base are 6 w/w % hydrogenated maltose starch syrup, 6 w/w % D-sorbitol, 6 w/w % glycerin, 1 w/w % propylene glycol, 0.02 w/w % propyl parahydroxybenzoate, and 65.38 w/w % water, per total amount of the composition.   
     
     
         16 . The Chinese herbal medical composition according to  claim 14 ,
 wherein the at least one pharmaceutically acceptable additive present in the base are 0.02 w/w % propyl parahydroxybenzoate and 84.38 w/w % water, per total amount of the composition.   
     
     
         17 . The Chinese herbal medical composition according to  claim 1 ,
 wherein the at least one pharmaceutically acceptable additive present in the base are at least one sweetening agent, at least one dispersion agent, and at least one preservative.   
     
     
         18 . The Chinese herbal medical composition according to  claim 17 , wherein:
 the at least one sweetening agent is selected from the group consisting of glucose, fructose, saccharin sodium, sucrose, D-sorbitol, D-mannitol, and hydrogenated maltose starch syrup,   the at least one dispersion agent is selected from the group consisting of glycerin, propylene glycol, and water, and   the preservative is propyl parahydroxybenzoate.   
     
     
         19 . A process for preparing the Chinese herbal medical composition according to  claim 1 , comprising:
 mixing the Hachimi-jio-gan, Keishi-bukuryo-gan, or Seijo-bofu-to with the carrageenan, the carob bean gum, the xanthan gum, and the at least one pharmaceutically acceptable additive, and   then adding warm water to the mixture or adding water to the mixture and further warming it,   wherein the resulting composition is stable.