Compositions comprising combinations of purified cannabinoids, with at least one flavonoid, terpene, or mineral

Abstract

Disclosed herein are new compositions having combinations of purified cannabinoids. One embodiment of this disclosure provides compositions having one or more purified cannabinoids in combination with a purified terpene. One embodiment of this disclosure provides compositions having one or more purified cannabinoids in combination with a purified flavonoid. One embodiment of this disclosure provides compositions having one or more purified cannabinoids in combination with a purified mineral.

We claim: 
     
         1 . A composition comprising:
 a first purified cannabinoid; and   a compound chosen from a second purified cannabinoid, a purified terpene, a purified flavonoid, and a purified mineral,   wherein the said composition is substantially free from cellulose.   
     
     
         2 . The composition of  claim 1 , comprising a purified mineral. 
     
     
         3 . The composition of  claim 2 , wherein the purified mineral is lithium. 
     
     
         4 . The composition of  claim 2 , consisting essentially of a first purified cannabinoid and a purified mineral. 
     
     
         5 . The composition of  claim 1 , comprising a purified terpene. 
     
     
         6 . The composition of  claim 5 , wherein the terpene is chosen from 7,8-dihydroionone, Acetanisole, Acetic Acid, Acetyl Cedrene, Anethole, Anisole, Benzaldehyde, Bergamotene (α-cis-Bergamotene) (α-trans-Bergamotene), Bisabolol (β-Bisabolol), Borneol, Butanoic/Butyric Acid, Cadinene (α-Cadinene) (γ-Cadinene), Cafestol, Caffeic acid, Camphene, Camphor, Capsaicin, Carene (Δ-3-Carene), Carotene, Carvacrol, Carvone, Dextro-Carvone, Laevo-Carvone, Caryophyllene (β-Caryophyllene), Caryophyllene oxide, Castoreum Absolute, Cedrene (α-Cedrene) (β-Cedrene), Cedrene Epoxide (α-Cedrene Epoxide), Cedrol, Cembrene, Chlorogenic Acid, Cinnamaldehyde (α-amyl-Cinnamaldehyde) (α-hexyl-Cinnamaldehyde), Cinnamic Acid, Cinnamyl Alcohol, Citronellal, Citronellol, Cryptone, Curcumene (α-Curcumene) (γ-Curcumene), Decanal, Dehydrovomifoliol, Diallyl Disulfide, Dihydroactinidiolide, Dimethyl Disulfide, Eicosane/Icosane, Elemene (β-Elemene), Estragole, Ethyl acetate, Ethyl Cinnamate, Ethyl maltol, Eucalyptol/1,8-Cineole, Eudesmol (α-Eudesmol) (μ-Eudesmol) (γ-Eudesmol), Eugenol, Euphol, Farnesene, Farnesol, Fenchol (β-Fenchol), Fenchone, Geraniol, Geranyl acetate, Germacrenes, Germacrene B, Guaia-1(10), 11-diene, Guaiacol, Guaiene (α-Guaiene), Gurjunene (α-Gurjunene), Herniarin, Hexanaldehyde, Hexanoic Acid, Humulene (α-Humulene) (β-Humulene), Ionol (3-oxo-α-ionol) (β-Ionol), Ionone (α-Ionone) (β-Ionone), Ipsdienol, Isoamyl acetate, Isoamyl Alcohol, Isoamyl Formate, Isoborneol, Isomyrcenol, Isopulegol, Isovaleric Acid, Isoprene, Kahweol, Lavandulol, Limonene, γ-Linolenic Acid, Linalool, Longifolene, α-Longipinene, Lycopene, Menthol, Methyl butyrate, 3-Mercapto-2-Methylpentanal, Mercaptan/Thiols, β-Mercaptoethanol, Mercaptoacetic Acid, Allyl Mercaptan, Benzyl Mercaptan, Butyl Mercaptan, Ethyl Mercaptan, Methyl Mercaptan, Furfuryl Mercaptan, Ethylene Mercaptan, Propyl Mercaptan, Thenyl Mercaptan, Methyl Salicylate, Methylbutenol, Methyl-2-Methylvalerate, Methyl Thiobutyrate, Myrcene (β-Myrcene), γ-Muurolene, Nepetalactone, Nerol, Nerolidol, Neryl acetate, Nonanaldehyde, Nonanoic Acid, Ocimene, Octanal, Octanoic Acid, P-cymene, Pentyl butyrate, Phellandrene, Phenylacetaldehyde, Phenylethanethiol, Phenylacetic Acid, Phytol, Pinene, β-Pinene, Propanethiol, Pristimerin, Pulegone, Retinol, Rutin, Sabinene, Sabinene Hydrate, cis-Sabinene Hydrate, trans-Sabinene Hydrate, Safranal, α-Selinene, α-Sinensal, β-Sinensal, β-Sitosterol, Squalene, Taxadiene, Terpin hydrate, Terpineol, Terpine-4-ol, α-Terpinene, γ-Terpinene, Terpinolene, Thiophenol, Thujone, Thymol, α-Tocopherol, Tonka Undecanone, Undecanal, Valeraldehyde/Pentanal, Verdoxan, α-Ylangene, Umbelliferone, or Vanillin. 
     
     
         7 . The composition of  claim 5 , wherein the terpene is chosen from Alpha-terpineol, Bergamotene (α-cis-Bergamotene) (α-trans-Bergamotene), Bisabolol (β-Bisabolol), Borneol, Camphor, Capsaicin, Carvacrol, Caryophyllene (β-Caryophyllene), Caryophyllene oxide, Cineole, Cinnamaldehyde (α-amyl-Cinnamaldehyde) (α-hexyl-Cinnamaldehyde), Cinnamyl Alcohol, Citronellal, Citronellol, Ethyl, Cinnamate, Eucalyptol/1,8-Cineole, Farnesol, Fenchol (β-Fenchol), Geranyl acetate, Germacrene B, Guaiene (α-Guaiene), Humulene (α-Humulene) (β-Humulene), Ionol (3-oxo-α-ionol) (β-Ionol), Ionone (α-Ionone) (β-Ionone), Isoamyl acetate, Isoprene, Kahweol, Laevo-Carvone, Lavandulol, Limonene, Linalool, Linalyl acetate, Luteolin, Lycopene, Menthol, Myrcene (β-Myrcene), Nerol, Nerolidol, Neryl acetate, P-cymene, Phytol, Pinene, Pristimerin, Retinol, Terpin hydrate, Terpineol, Terpinol-4-ol, Terpinolene, Thujone, Thymol, or Vanillin. 
     
     
         8 . The composition of  claim 5 , comprising of Cannabigerolic Acid (CBGA), Cannabigerolic Acid monomethylether (CBGAM), Cannabigerol (CBG), Cannabigerol monomethylether (CBGM), Cannabigerovarinic Acid (CBGVA), Cannabigerovarin (CBGV), Cannabichromenic Acid (CBCA), Cannabichromene (CBC), Cannabichromevarinic Acid (CBCVA), Cannabichromevarin (CBCV), Cannabidiolic Acid (CBDA), Cannabidiol (CBD), Cannabidiol monomethylether (CBDM), Cannabidiol-C 4  (CBD-C 4 ), Cannabidivarinic Acid (CBDVA), Cannabidivarin (CBDV), Cannabidiorcol (CBD-C 1 ), Tetrahydrocannabinolic acid A (THCA-A), Tetrahydrocannabinolic acid B (THCA-B), Tetrahydrocannabinol (THC), Tetrahydrocannabinolic acid C 4  (THCA-C 4 ), Tetrahydrocannbinol C 4  (THC-C 4 ), Tetrahydrocannabivarinic acid (THCVA), Tetrahydrocannabivarin (THCV), Tetrahydrocannabiorcolic acid (THCA-C 1 ), Tetrahydrocannabiorcol (THC-C 1 ), Delta-7-cis-iso-tetrahydrocannabivarin, Δ 8 -tetrahydrocannabinolic acid (Δ8-THCA), Δ 8 -tetrahydrocannabinol (Δ 8 -THC), Cannabicyclolic acid (CBLA), Cannabicyclol (CBL), Cannabicyclovarin (CBLV), Cannabielsoic acid A (CBEA-A), Cannabielsoic acid B (CBEA-B), Cannabielsoin (CBE), Cannabinolic acid (CBNA), Cannabinol (CBN), Cannabinol methylether (CBNM), Cannabinol-C 4  (CBN-C 4 ), Cannabivarin (CBV), Cannabino-C 2  (CBN-C 2 ), Cannabiorcol (CBN-C 1 ), Cannabinodiol (CBND), Cannabinodivarin (CBDV), Cannabitriol (CBT), 10-Ethoxy-9-hydroxy-Δ 6a -tetrahydrocannabinol, 8,9-Dihydroxy-Δ 6a(10a) -tetrahydrocannabinol (8,9-Di-OH-CBT-C 5 ), Cannabitriolvarin (CBTV), Ethoxy-cannabitriolvarin (CBTVE), Dehydrocannabifuran (DCBF), Cannbifuran (CBF), Cannabichromanon (CBCN), Cannabicitran (CBT), 10-Oxo-Δ 6a(10a) -tetrahydrocannabinol (OTHC), Δ 9 -cis-tetrahydrocannabinol (cis-THC), Cannabiripsol (CBR), 3,4,5,6-tetrahydro-7-hydroxy-alpha-alpha-2-trimethyl-9-n-propyl-2,6-methano-2H-1-benzoxocin-5-methanol (OH-iso-HHCV), Trihydroxy-delta-9-tetrahydrocannabinol (triOH-THC), Isocanabinoids, and Epigallocatechin gallate. 
     
     
         9 . The composition of  claim 8 , wherein the first purified cannabinoid is chosen from Tetrahydrocannabinol (THC), Tetrahydrocannabivarin (THCV), Cannabichromene (CBC), Cannabichromanon (CBCN), Cannabidiol (CBD), Cannabielsoin (CBE), Cannabidivarin (CBDV), Cannbifuran (CBF), Cannabicyclol (CBL), Cannabinol (CBN), Cannabinodiol (CBND), Cannabitriol (CBT), Cannabivarin (CBV), and Isocanabinoids. 
     
     
         10 . The composition of  claim 9 , comprising a first purified cannabinoid chosen from Cannabigerolic Acid (CBGA), Cannabigerolic Acid monomethylether (CBGAM), Cannabigerol (CBG), Cannabigerol monomethylether (CBGM), Cannabigerovarinic Acid (CBGVA), Cannabigerovarin (CBGV), Cannabichromenic Acid (CBCA), Cannabichromene (CBC), Cannabichromevarinic Acid (CBCVA), Cannabichromevarin (CBCV), Cannabidiolic Acid (CBDA), Cannabidiol (CBD), Cannabidiol monomethylether (CBDM), Cannabidiol-C 4  (CBD-C 4 ), Cannabidivarinic Acid (CBDVA), Cannabidivarin (CBDV), Cannabidiorcol (CBD-C 1 ), Tetrahydrocannabinolic acid A (THCA-A), Tetrahydrocannabinolic acid B (THCA-B), Tetrahydrocannabinol (THC), Tetrahydrocannabinolic acid C 4  (THCA-C 4 ), Tetrahydrocannbinol C 4  (THC-C 4 ), Tetrahydrocannabivarinic acid (THCVA), Tetrahydrocannabivarin (THCV), Tetrahydrocannabiorcolic acid (THCA-C 1 ), Tetrahydrocannabiorcol (THC-C 1 ), Delta-7-cis-iso-tetrahydrocannabivarin, Δ 8 -tetrahydrocannabinolic acid (Δ8-THCA), Δ 8 -tetrahydrocannabinol (Δ 8 -THC), Cannabicyclolic acid (CBLA), Cannabicyclol (CBL), Cannabicyclovarin (CBLV), Cannabielsoic acid A (CBEA-A), Cannabielsoic acid B (CBEA-B), Cannabielsoin (CBE), Cannabinolic acid (CBNA), Cannabinol (CBN), Cannabinol methylether (CBNM), Cannabinol-C 4  (CBN-C 4 ), Cannabivarin (CBV), Cannabino-C 2  (CBN-C 2 ), Cannabiorcol (CBN-C 1 ), Cannabinodiol (CBND), Cannabinodivarin (CBDV), Cannabitriol (CBT), 10-Ethoxy-9-hydroxy-Δ 6a -tetrahydrocannabinol, 8,9-Dihydroxy-Δ 6a(10a) -tetrahydrocannabinol (8,9-Di-OH-CBT-C 5 ), Cannabitriolvarin (CBTV), Ethoxy-cannabitriolvarin (CBTVE), Dehydrocannabifuran (DCBF), Cannbifuran (CBF), Cannabichromanon (CBCN), Cannabicitran (CBT), 10-Oxo-Δ 6a(10a) -tetrahydrocannabinol (OTHC), Δ 9 -cis-tetrahydrocannabinol (cis-THC), Cannabiripsol (CBR), 3,4,5,6-tetrahydro-7-hydroxy-alpha-alpha-2-trimethyl-9-n-propyl-2,6-methano-2H-1-benzoxocin-5-methanol (OH-iso-HHCV), Trihydroxy-delta-9-tetrahydrocannabinol (triOH-THC), Yangonin, Isocanabinoids, Epigallocatechin gallate, Dodeca-2E,4E,8Z,10Z-tetraenoic acid isobutylamide, or Dodeca-2E,4E-dienoic acid isobutylamide; and
 a second purified cannabinoid chosen from Cannabigerolic Acid (CBGA), Cannabigerolic Acid monomethylether (CBGAM), Cannabigerol (CBG), Cannabigerol monomethylether (CBGM), Cannabigerovarinic Acid (CBGVA), Cannabigerovarin (CBGV), Cannabichromenic Acid (CBCA), Cannabichromene (CBC), Cannabichromevarinic Acid (CBCVA), Cannabichromevarin (CBCV), Cannabidiolic Acid (CBDA), Cannabidiol (CBD), Cannabidiol monomethylether (CBDM), Cannabidiol-C 4  (CBD-C 4 ), Cannabidivarinic Acid (CBDVA), Cannabidivarin (CBDV), Cannabidiorcol (CBD-C 1 ), Tetrahydrocannabinolic acid A (THCA-A), Tetrahydrocannabinolic acid B (THCA-B), Tetrahydrocannabinol (THC), Tetrahydrocannabinolic acid C 4  (THCA-C 4 ), Tetrahydrocannbinol C 4  (THC-C 4 ), Tetrahydrocannabivarinic acid (THCVA), Tetrahydrocannabivarin (THCV), Tetrahydrocannabiorcolic acid (THCA-C 1 ), Tetrahydrocannabiorcol (THC-C 1 ), Delta-7-cis-iso-tetrahydrocannabivarin, Δ 8 -tetrahydrocannabinolic acid (Δ8-THCA), Δ 8 -tetrahydrocannabinol (Δ 8 -THC), Cannabicyclolic acid (CBLA), Cannabicyclol (CBL), Cannabicyclovarin (CBLV), Cannabielsoic acid A (CBEA-A), Cannabielsoic acid B (CBEA-B), Cannabielsoin (CBE), Cannabinolic acid (CBNA), Cannabinol (CBN), Cannabinol methylether (CBNM), Cannabinol-C 4  (CBN-C 4 ), Cannabivarin (CBV), Cannabino-C 2  (CBN-C 2 ), Cannabiorcol (CBN-C 1 ), Cannabinodiol (CBND), Cannabinodivarin (CBDV), Cannabitriol (CBT), 10-Ethoxy-9-hydroxy-Δ 6a -tetrahydrocannabinol, 8,9-Dihydroxy-Δ 6a(10a) -tetrahydrocannabinol (8,9-Di-OH-CBT-C 5 ), Cannabitriolvarin (CBTV), Ethoxy-cannabitriolvarin (CBTVE), Dehydrocannabifuran (DCBF), Cannbifuran (CBF), Cannabichromanon (CBCN), Cannabicitran (CBT), 10-Oxo-Δ 6a(10a) -tetrahydrocannabinol (OTHC), Δ 9 -cis-tetrahydrocannabinol (cis-THC), Cannabiripsol (CBR), 3,4,5,6-tetrahydro-7-hydroxy-alpha-alpha-2-trimethyl-9-n-propyl-2,6-methano-2H-1-benzoxocin-5-methanol (OH-iso-HHCV), Trihydroxy-delta-9-tetrahydrocannabinol (triOH-THC), Yangonin, Isocanabinoids, Epigallocatechin gallate, Dodeca-2E,4E,8Z,10Z-tetraenoic acid isobutylamide, or Dodeca-2E,4E-dienoic acid isobutylamide. 
 
     
     
         11 . The composition of  claim 1 , comprising a purified flavonoid. 
     
     
         12 . The composition of  claim 11 , wherein the flavonoid is chosen from phenolic acids, stilbenoids, dihydroflavonols, anthocyanins, anthocyanidins, polyphenols, tannins, flavones, flavan-3-ols, Flavan-4-ol, Flavan-3,4-diol flavonols, stilbenoids, phytochemicals, antioxidants, homoisoflavonoids, phenylpropanoids, Phloroglucinols coumarins, Phenolic acids, Naphthodianthrones, Steroid glycosides, bioflavonoids, isoflavonoids, and neoflavonoids. 
     
     
         13 . The composition of  claim 11 , wherein the flavonoid is chosen from Adenosine, Adhyperforin, amentoflavone, Anandamide, Apigenin, Cannaflavin B, Catechin (C), Catechin 3-gallate (Cg), Chlorogenic acid, cichoric acid, caftaric acid, Daidzein, Delphinidin, Eleutherosides, Epicatechin 3-gallate (ECg), Epicatechins, Epicatechin, epigallocatechin, myricetin, Oxalic acid, Pelargonidin, Tannin, Theaflavin-3-gallate, Theanine, Theobromine, Theophylline, Tryptophan, Tyramine, Xanthine, Caffeine, Cannaflavin A, Cannaflavin B, Catechin (C), Catechin 3-gallate (Cg), Epicatechin 3-gallate (ECg), Epicatechins (Epicatechin (EC)), epigallocatechin, Epigallocatechin (EGC), Epigallocatechin 3-gallate (EGCg), Gallocatechin (GC), Gallocatechin 3-gallate (GCg)), Gamma amino butyric acid, Genistein,  Ginkgo biloba , Ginsenosides, Quercetin, Quercitrin, or Rutin. 
     
     
         14 . The composition of  claim 11 , wherein the purified flavonoid is chosen from Caffeine, Cannaflavin A, Cannaflavin B, Catechin (C), Catechin 3-gallate (Cg), Epicatechin 3-gallate (ECg), Epicatechins (Epicatechin (EC)), epigallocatechin, Epigallocatechin (EGC), Epigallocatechin 3-gallate (EGCg), Gallocatechin (GC), Gallocatechin 3-gallate (GCg)), Gamma amino butyric acid, Genistein,  Ginkgo biloba , Ginsenosides, Quercetin, Quercitrin, or Rutin. 
     
     
         15 . The composition of  claim 1 , comprising Cannabichromene and at least one purified terpene chosen from Linalool, Borneol, Elemene, Mycerne, Nerolidol, Phytol, Terpinolene, Bornyl acetate, Terpineol. 
     
     
         16 . The composition of  claim 1 , comprising Cannabigerol and at least one purified terpene chosen from Linalool, Borneol, elemene, Mycerne, Nerolidol, Phytol, Terpinolene, Bornyl acetate, Terpineol. 
     
     
         17 . The composition of  claim 1 , comprising Cannabinol and at least one compound chosen from Linalool, Borneol, elemene, Mycerne, Nerolidol, Phytol, Terpinolene, Bornyl acetate, Terpineol. 
     
     
         18 . The composition of  claim 1 , comprising Tetrahydrocannabivarin and at least one compound chosen from Pinene, Bornyl acetate, Limonene, Caryophyllene, and Sabinene. 
     
     
         19 . The composition of  claim 1 , comprising a cannabinoid chosen from Tetrahydrocannabinol and Cannabichromene and at least one compound chosen from Caryophyllene, Pinene, Bornyl acetate, Cineole, Limonene, Caryophyllene, Pinene, Bornyl acetate. 
     
     
         20 . The composition of  claim 1 , comprising a cannabinoid chosen from Tetrahydrocannabinol or Tetrahydrocannabivarin and at least one compound chosen from Limonene and Caryophyllene. 
     
     
         21 . The composition of  claim 1 , comprising a cannabinoid chosen from Tetrahydrocannabinol or Tetrahydrocannabivarin and at least one compound chosen from Limonene, Terpinolene, Pulegone. 
     
     
         22 . The compound of  claim 1 , comprising Cannabichromene and at least one compound chosen from Linalool, Myrcene, Terpineol. 
     
     
         23 . The compound of  claim 1 , comprising Cannabigerol and Myrcene. 
     
     
         24 . The compound of  claim 1 , comprising Cannabidiol and Myrcene. 
     
     
         25 . The compound of  claim 1 , comprising Cannabinol and at least one compound chosen from Linalool, Terpineol. 
     
     
         26 . The compound of  claim 1 , comprising Tetrahydrocannabivarin and at least one compound chosen from Cineole, Pinene, Bornyl acetate, Limonene, Caryophyllene, and Sabinene. 
     
     
         27 . The compound of  claim 1 , comprising at least one cannabinoid chosen from Tetrahydrocannabinol or Cannabidiol and at least one terpene chosen from Caryophyllene, Pinene, Bornyl acetate, Cineole, Limonene, Pulegone, Linalool, Hypericin, Pseudohypericin, Hyperforin, Anethole. 
     
     
         28 . The compound of  claim 1 , comprising Tetrahydrocannabinol or Tetrahydrocannabivarin and at least one compound chosen from Pulegone, Cineole, Anethole. 
     
     
         29 . The compound of  claim 1 , comprising Tetrahydrocannabinol and Myrcene. 
     
     
         30 . The compound of  claim 1 , comprising Tetrahydrocannabivarin and Myrcene.