Fungicidal compositions

Abstract

The present invention provides a composition comprising a combination of components A) and B), wherein component A) is a compound of formula (I) and the component (B) is a further fungicide, insecticide or herbicide.

What is claimed is: 
     
         1 . A compound of formula (I) 
       
         
           
           
               
               
           
         
         wherein 
         R 1  and R 2  are each independently selected from hydrogen and C 1 -C 4  alkyl; 
         or R 1  and R 2  together with the nitrogen atom to which they are connected form pyrrolidine or piperidine; 
         R 3  represents hydrogen, halogen, cyano, C 1 -C 4  alkyl, C 1 -C 4  haloalkyl, C 2 -C 4  alkenyl, C 2 -C 4  alkynyl, C 1 -C 4  alkoxy, C 3 -C 6  cycloalkyl, amino, C 1 -C 2  alkylamino, di(C 1 -C 6 alkyl)amino, pyrrolidino, imidazolino, triazolino, formyl, phenyl, C 2 -C 4  alkylcarbonyl, C 1 -C 6  alkylthio, C 1 -C 6  alkylsulfinyl, C 1 -C 6  alkylsulfonyl or C 1 -C 6  hydroxyalkyl; 
         R 4  is selected from fluorine, chlorine, bromine, C 1 -C 4  alkyl, C 1 -C 4  alkenyl, C 1 -C 4  haloalkyl, C 1 -C 4  alkoxy and C 3 -C 6  cycloalkyl; 
         R 5  is selected from G 5 , G 6 -G 7  and G 10 -G 11 ; 
         G 5  is C 3 -C 7  cycloalkyl, which is substituted by one or more groups independently selected from ethyl, n-propyl, iso-propyl, n-butyl, iso-butyl, sec-butyl, tert-butyl, n-pentyl, —CH(CH 3 )—CH 2 —CH 2 —CH 3 , —CH—CH(CH 3 )—CH 2 —CH 3 , —CH 2 —CH 2 —CH(CH 3 )—CH 3 , —CH 2 —CH 2 —CH(CH 3 ) 2 , —CH(CH 3 )—CH(CH 3 ) 2 , C 2 -C 6  haloalkyl, C 1 -C 6  alkoxy, C 3 -C 4 -alkenyloxy, phenoxy and C 1 -C 6  alkylthio; 
         G 6  is phenyl, which must be substituted by at least one fluorine and is optionally further substituted by one or more groups independently selected from halogen, CN, C 1 -C 6  alkyl, C 1 -C 6  haloalkyl, C 3 -C 6  cycloalkyl, C 2 -C 6  alkenyl, C 2 -C 6  alkynyl, C 1 -C 6  alkoxy, C 3 -C 6  alkenyloxy, C 3 -C 6  alkynyloxy and C 1 -C 6  alkylthio; 
         G 7  is methylene; 
         G 10  is phenyl, which is optionally substituted by one or more groups independently selected from halogen, CN, OH, SH, CHO, C 1 -C 6  alkyl, C 1 -C 6  haloalkyl, C 3 -C 6  cycloalkyl, C 2 -C 6  alkenyl, C 2 -C 6  haloalkenyl, C 2 -C 6  alkynyl, C 1 -C 6  alkoxy, C 1 -C 6  haloalkoxy, C 3 -C 6  alkenyloxy, C 3 -C 6  alkynyloxy, C 3 -C 6  cycloalkoxy, phenyl, C 1 -C 6  alkylthio, C 1 -C 6  alkylsulfinyl and C 1 -C 6  alkylsulfonyl. 
         G 11  is methylene substituted by at least one group independently selected from C 1 -C 4  alkyl, C 1 -C 4  haloalkyl, CN, C 1 -C 4  alkoxy and C 1 -C 4  haloalkoxy; 
         R 6  is hydrogen; 
         R 7  is selected from hydrogen and C 1 -C 4  alkyl; 
         or an agronomically acceptable salt, metallic complex, metalloidic complex, isomer, structural isomer, stereo-isomer, diastereoisomer, enantiomer, tautomer, or N-oxide thereof. 
       
     
     
         2 . A compound of formula (I) according to  claim 1  wherein R 1  and R 2  are each C 1 -C 4  alkyl;
 R 3  represents hydrogen, halogen, cyano, C 1 -C 4  alkyl, C 1 -C 4  haloalkyl, C 2 -C 4  alkenyl, C 2 -C 4  alkynyl, C 1 -C 4  alkoxy, C 3 -C 6  cycloalkyl, C 1 -C 4  alkylthio, C 1 -C 4  alkylsulfinyl or C 1 -C 4  alkylsulfonyl; 
 R 4  is selected from methyl, ethyl, methoxy, fluorine and chlorine; 
 R 6  is hydrogen; 
 R 7  is hydrogen or C 1 -C 4  alkyl. 
 
     
     
         3 . A compound of formula (I) according to  claim 1  wherein R 1  and R 2  are each independently selected from methyl, ethyl and isopropyl;
 R 3  represents hydrogen, halogen, C 1 -C 4  alkyl, C 1 -C 4  haloalkyl, cyclopropyl, ethynyl or C 1 -C 4  alkoxy; 
 R 4  is selected from methyl, methoxy, fluorine and chlorine; 
 R 6  is hydrogen; 
 R 7  is hydrogen. 
 
     
     
         4 . A compound of formula (I) according to  claim 1  wherein
 R 1  is methyl; 
 R 2  is ethyl; 
 R 3  is selected from hydrogen, bromine, iodine, methyl, CHF 2 , cyclopropyl, ethynyl and methoxy; 
 R 4  is methyl; 
 R 6  is hydrogen; 
 R 7  is hydrogen. 
 
     
     
         5 . A compound of formula (I) according to  claim 1  wherein R 5  is G 5 ; and
 G 5  is C 6  cycloalkyl, which is substituted by one or more groups independently selected from ethyl, n-propyl, iso-propyl, n-butyl, iso-butyl, sec-butyl, tert-butyl, n-pentyl, —CH(CH 3 )—CH 2 —CH 2 —CH 3 , —CH—CH(CH 3 )—CH 2 —CH 3 , —CH 2 —CH 2 —CH(CH 3 )—CH 3 , —CH 2 —CH 2 —CH(CH 3 ) 2  and —CH(CH 3 )—CH(CH 3 ) 2 . 
 
     
     
         6 . A compound according to  claim 1  wherein R 5  is G 6 -G 7 ;
 G 6  is phenyl, which must be substituted by at least one fluorine and is optionally further substituted by one or more halogen, CHF 2 , CF 3  and C 1 -C 4  alkyl; and 
 G 7  is methylene. 
 
     
     
         7 . A compound according to  claim 1  wherein R 5  is G 10 -G 11 ;
 G 10  is phenyl, which is optionally substituted by one or more groups independently selected from halogen, CN, methyl, ethyl, n-propyl, iso-propyl, methoxy, CHF 2 , CF 3  and OCHF 2  and 
 G 11  is methylene substituted by at least one group independently selected from methyl, CF 3  and ethyl. 
 
     
     
         8 . A compound according to  claim 1  wherein
 R 1  is methyl; 
 R 2  is ethyl; 
 R 3  is selected from hydrogen, bromine, iodine, methyl, CHF 2 , cyclopropyl, ethynyl and methoxy; 
 R 4  is methyl; 
 R 5  is selected from G 5 , G 6 -G 7  and G 10 -G 11 ; 
 G 5  is C 6  cycloalkyl, which is substituted by one or more groups independently selected from ethyl, n-propyl, iso-propyl, n-butyl, iso-butyl, sec-butyl, tert-butyl, n-pentyl, —CH(CH 3 )—CH 2 —CH 2 —CH 3 , —CH—CH(CH 3 )—CH 2 —CH 3 , —CH 2 —CH 2 —CH(CH 3 )—CH 3 , —CH 2 —CH 2 —CH(CH 3 ) 2  and —CH(CH 3 )—CH(CH 3 ) 2 ; 
 G 6  is phenyl, which must be substituted by at least one fluorine and is optionally further substituted by one or more halogen, CHF 2 , CF 3  and C 1 -C 4  alkyl; 
 G 7  is methylene; 
 G 10  is phenyl, which is optionally substituted by one or more groups independently selected from halogen, CN, methyl, ethyl, n-propyl, iso-propyl, methoxy, CHF 2 , CF 3  and OCHF 2 ; 
 G 11  is methylene substituted by at least one group independently selected from methyl, CF 3  and ethyl; 
 R 6  is hydrogen; and 
 R 7  is hydrogen; 
 and agronomically acceptable salts/metallic complexes/metalloidic complexes/isomers/structural isomers/stereo-isomers/diastereoisomers/enantiomers/tautomers/N-oxides of those compounds. 
 
     
     
         9 . A fungicidal composition comprising a compound of formula (I) according to any one of  claims 1  to  8 , an inert carrier and, optionally, an adjuvant. 
     
     
         10 . A fungicidal composition, comprising a combination of components A) and B), wherein component A) is a compound of formula (I) as defined in any of  claims 1  to  8 , and agronomically acceptable salts/metallic complexes/metalloidic complexes/isomers/structural isomers/stereo-isomers/diastereoisomers/enantiomers/tautomers/N-oxides of those compounds, and component B) is a strobilurin fungicide, a sterol biosynthesis inhibitor, a triazole fungicide, a pro-triazole fungicide, a DMI fungicide, a SDHI fungicide, or a compound selected from the group consisting of Chlorothalonil, Fludioxonil, Cyprodinil, Mandipropamid, Fluazinam, Procymedone, Carbendazim, Abamectin, Clothianidin, Emamectin benzoate, Imidacloprid, Tefluthrin, Mefenoxam, Orocymedone, Thiamethoxam, Lambda-cyhalothrin, Gamma-cyhalothrin, Profenofos, Lufenuron, Diflubenzuron, Cypermethrin, Novaluron, Bifenthrin, Methomyl, Chlopyrifos, Methamidophos, Endosulfan, Betacyfluthrin, Triflumuron, Teflubenzuron, SulcotrioneAcephat, Glyphosate, Glufosinate, Mesotrione, Tembotrione, Sulcotrione, Auxins, Trinexapac-ethyl, Prohexadione-Ca, Paclobutrazol, Acibenzolar-S-methyl, Methyl-Jasmonate, Cis-Jasmone, Manganese, Cyflufenamid, Tebufloquin and Copper. 
     
     
         11 . A method of controlling phytopathogenic diseases on useful plants or on propagation material thereof, which comprises applying to the useful plants, the locus thereof or propagation material thereof a compound of formula (I) according to any one of  claims 1  to  8  or a fungicidal composition according to  claim 9  or  claim 10 . 
     
     
         12 . A method of protecting natural substances of plant origin, which have been taken from their natural life cycle, and/or their processed forms, which comprises applying to said natural substances of plant origin or their processed forms a compound of formula (I) according to any one of  claims 1  to  8  or a fungicidal composition according to  claim 9  or  claim 10 .