Nasal Delivery Device and Methods of Use

Abstract

The present invention provides a drug delivery system that includes a housing configured to contain one or more dispensers. Each dispenser includes an activation mechanism, a nozzle configured to direct the medicament to a predetermined area in the nasal passageway. The nozzles may be configured to create a spray pattern that is about 50-degrees to direct the delivery of a medicament to the sphenopalatine ganglion.

What is claimed is: 
     
         1 . A drug delivery system comprising:
 a housing configured to contain one or more unit dispensers;   a user activation mechanism, effective when activated, to engage a drug delivery mechanism to expel medicament from a dispenser; and   a nozzle configured to direct the medicament to a predetermined area in the nasal passageway.   
     
     
         2 . The drug delivery system of  claim 1  wherein said housing is comprised of two mirror image dispensers. 
     
     
         3 . The drug delivery system of  claim 2  wherein each of said dispensers includes an activation mechanism located medially to the user. 
     
     
         4 . The drug delivery system of  claim 2  wherein each of said dispensers includes a nozzle configured to direct a medicament to the sphenopalatine ganglion. 
     
     
         5 . The drug delivery system of  claim 4  wherein each of said dispensers includes a curved nozzle configured to direct a medicament to the sphenopalatine ganglion. 
     
     
         6 . The drug delivery system of  claim 4  wherein each of said nozzles extend from an edge that forms a line that may be positioned along a user's upper lip, said edge acts as a guide. 
     
     
         7 . The drug delivery system of  claim 6  wherein each of said dispensers include a shoulder, said shoulder and said edge act as a stop that prevents further insertion of the nozzle. 
     
     
         8 . The drug delivery system of  claim 7  wherein each of said nozzles are configured to create a spray pattern that is about 50-degrees to direct the delivery of a medicament to the sphenopalatine ganglion. 
     
     
         9 . The drug delivery system of  claim 8  wherein each of said nozzles are further configured to form an arch of about 61-degrees. 
     
     
         10 . The drug delivery system of  claim 9  wherein each of said nozzles are rotated  19 -degrees to provide approximately 90-degrees of total rotation from a vertical position to direct the delivery of a medicament to the sphenopalatine ganglion. 
     
     
         11 . The drug delivery system of  claim 1  wherein each of said nozzles are conical in shape so that upon insertion into the nasal cavity, a seal is formed such no medicament escapes. 
     
     
         12 . The drug delivery system of  claim 11  wherein said activation mechanism is positioned such that when a user grasps the dispenser, the user's thumb may be used to actuate the activation mechanism. 
     
     
         13 . The drug delivery system of  claim 12  wherein said activation mechanism is directed toward the user. 
     
     
         14 . A method for delivering a medication to the sphenopalatine ganglion, which comprises:
 providing a housing having releasably connected first and second dispensers, each of said dispensers including a nozzle disposed between a pair of shoulders and said nozzle configured to form an arch of about 61-degrees;   disconnecting said dispensers from another and using each respective dispenser to deliver a unit dosage by inserting a nozzle until said shoulders prevent further insertion;   rotating said dispenser approximately 19 degrees to direct the medication to the sphenopalatine ganglion.   
     
     
         15 . The method of  claim 14  wherein each of said nozzles are configured to create a spray pattern that is about 50-degrees to direct the delivery of a medicament to the sphenopalatine ganglion. 
     
     
         16 . The method of  claim 14  wherein each of said nozzles are conical in shape so that upon insertion, a seal is formed such that when the device is activated spray is contained in the nasal cavity. 
     
     
         17 . The method of  claim 14  wherein said dispensers include an activation mechanism that is positioned such that when a user grasps a dispenser, the user's thumb may be used to actuate the device. 
     
     
         18 . The method of  claim 14  wherein said nozzles generate a vortex of fluid. 
     
     
         19 . The drug delivery system of  claim 1  wherein each of said nozzles creates a vortex.