Inspection tool for nucleic acid chromatography

Abstract

An inspection tool for nucleic acid chromatography includes an elongated porous sheet and a backing member. The porous sheet has a surface including a detection surface that has a strip-shaped indication portion where a nucleic acid probe for capturing the target nucleic acid is fixed. The backing member has an attached surface in a concave shape. The porous sheet has a warped shape following the concave shape of the attached surface.

1 .- 9 . (canceled) 
     
     
         10 . An inspection tool for nucleic acid chromatography, comprising:
 an elongated porous sheet that expands a sample liquid containing a target nucleic acid and detects the target nucleic acid so as to indicate the detection; and   a backing member where the porous sheet is attached, wherein   the porous sheet has a surface including a detection surface, the detection surface including a strip-shaped indication portion where a nucleic acid probe for capturing the target nucleic acid is fixed, the indication portion extending at an angle to intersect with a longitudinal direction of the porous sheet, and   the detection surface has a convex shape.   
     
     
         11 . the inspection tool for nucleic acid chromatography according to  claim 10 , wherein in the cross section perpendicular to the longitudinal direction of the porous sheet, the convex shape of the detection surface is smoothly curved. 
     
     
         12 . The inspection tool for nucleic acid chromatography according to  claim 10 , wherein
 in the indication portion, the nucleic acid probe is fixed at a higher density in a region having a predetermined width from each of both the end portions of the indication portion toward a center compared with in a residual region in the same indication portion.   
     
     
         13 . The inspection tool for nucleic acid chromatography according to  claim 10 , wherein
 in the indication portion, the porous sheet has a smaller average aperture diameter in a region having a predetermined width from each of both the end portions of the indication portion toward a center compared with in a residual region in the same indication portion.   
     
     
         14 . The inspection tool for nucleic acid chromatography according to  claim 10 , wherein
 the indication portion comprises a first end portion, a second end portion, and a connecting portion which connects the first and second end portion, and wherein   in cross section the connecting portion projects away from the side attached to the backing member to with respect to a reference line connecting both the end portions.   
     
     
         15 . The inspection tool for nucleic acid chromatography according to  claim 14 , wherein the porous sheet is brought into close contact with the backing member, so as to form a shape where the detection surface projects away from the backing member. 
     
     
         16 . The inspection tool for nucleic acid chromatography according to  claim 10 , wherein a center portion of the porous sheet along the longitudinal direction is thicker than side portions of the porous sheet. 
     
     
         17 . The inspection tool for nucleic acid chromatography according to  claim 10 , wherein the detection surface has a hog-backed shape.