US2016143922A1PendingUtilityA1
Anti-flush compositions
Est. expiryOct 28, 2031(~5.3 yrs left)· nominal 20-yr term from priority
Inventors:Joseph Habboushe
A61P 3/06A61P 9/10A61K 9/209A61K 9/0002A61K 31/616A61K 31/44A61K 31/455A61K 9/0056A61K 9/0053
40
PatentIndex Score
0
Cited by
0
References
0
Claims
Abstract
Disclosed are pharmaceutical compositions having a portion of aspirin for intraoral release and another aspirin for gastrointestinal release. The compositions can further include niacin. Methods of using such compositions to treat diseases or conditions suitably treated by niacin are also provided which result in reduced flushing.
Claims
exact text as granted — not AI-modified1 . A pharmaceutical composition comprising a first portion comprising a first subtherapeutic amount of aspirin, and a second portion comprising a second subtherapeutic amount of aspirin, wherein, upon oral administration to a subject, the first portion disintegrates or dissolves intraorally providing rapid release of the aspirin of the first portion, and the second portion is substantially more difficult than the first portion to disintegrate or dissolve intraorally but is ingestible and releasable in the gastrointestinal track of the subject.
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