Vascular remodeling device

Abstract

A generally spherical vascular remodeling device is permanently positionable at a junction of afferent and efferent vessels of a bifurcation having an aneurysm. After positioning the device at the junction to substantially conform the device to the shape of the junction, the device acts as a scaffolding to inhibit herniation of objects out of the aneurysm and the device permits perfusion to the efferent vessels. Positioning the device may include deployment and mechanical or electrolytic release from a catheter. Embolic material may be inserted in the aneurysm before or after positioning the device. The device may have a first end, a second end substantially opposite to the first end, and a plurality of filaments extending between and coupled at the first end and the second end. Such devices may be football shaped, pumpkin shaped, or twisted. The device may include a plurality of loops forming a generally spherical shape.

1 - 26 . (canceled) 
     
     
         27 . A vascular remodeling device comprising:
 a plurality of filaments, each filament extending between a proximal end and a distal end to form a generally spherical shape having an outer periphery;   a plurality of proximal struts integral with the filaments and connecting adjacent pairs of the filaments at the proximal ends of the filaments and at a proximal location outside the outer periphery of the generally spherical shape;   a plurality of distal struts integral with the filaments and interconnecting adjacent pairs of the filaments at the distal ends of the filaments and at a distal location substantially opposite to the proximal location along a longitudinal axis of the device and outside the outer periphery of the generally spherical shape;   a proximal sleeve positioned around the proximal ends of the filaments; and   a distal sleeve positioned around the distal ends of the filaments.   
     
     
         28 . The vascular remodeling device of  claim 27 , wherein each adjacent pair of the filaments are connected by a pair of distal struts at the distal ends. 
     
     
         29 . The vascular remodeling device of  claim 27 , wherein each adjacent pair of the filaments are connected by a pair of proximal struts at the proximal ends. 
     
     
         30 . The vascular remodeling device of  claim 27 , wherein the plurality of filaments are unattached to each other between the proximal ends to the distal ends. 
     
     
         31 . The vascular remodeling device of  claim 27 , wherein the proximal sleeve and the distal sleeve are radiopaque markers. 
     
     
         32 . The vascular remodeling device of  claim 27 , wherein the filaments comprise shape-memory material. 
     
     
         33 . The vascular remodeling device of  claim 27 , wherein at least one of the filaments comprises a radiopaque material. 
     
     
         34 . The vascular remodeling device of  claim 27 , wherein at least one of the filaments comprises a radiopaque material at least partially wrapped around a self-expanding material. 
     
     
         35 . The vascular remodeling device of  claim 27 , wherein at least one of the filaments comprises a self-expanding material with a radiopaque core or a radiopaque coating. 
     
     
         36 . The vascular remodeling device of  claim 27 , wherein a proximal porosity distally increases between the proximal ends and an equator of the shape and wherein a distal porosity distally decreases between the equator and the distal ends. 
     
     
         37 . A system comprising:
 a catheter;   a delivery lead; and   the vascular remodeling device of  claim 27 , the vascular remodeling device being detachably connected to the delivery lead and housed within the catheter.   
     
     
         38 . A vascular remodeling device comprising:
 a plurality of filaments, each filament extending between a proximal end and a distal end to form a shape, the filaments having proximal sections extending distally and radially outwardly from the proximal ends to an equator of the shape, the filaments having distal sections extending (i) distally and radially inwardly from the equator to bends and (ii) proximally and radially inwardly from the bends toward the distal ends;   a proximal sleeve positioned around the proximal ends of the filaments; and   a distal sleeve positioned around the distal ends of the filaments, the distal sleeve extending farther distally than the bends along a longitudinal axis of the device.   
     
     
         39 . The vascular remodeling device of  claim 38 , wherein the plurality of filaments are unattached to each other between the proximal ends to the distal ends 
     
     
         40 . The vascular remodeling device of  claim 38 , wherein the proximal sleeve and the distal sleeve are radiopaque markers. 
     
     
         41 . The vascular remodeling device of  claim 38 , wherein the filaments comprise shape-memory material. 
     
     
         42 . The vascular remodeling device of  claim 38 , wherein at least one of the filaments comprises a radiopaque material. 
     
     
         43 . The vascular remodeling device of  claim 38 , wherein at least one of the filaments comprises a radiopaque material at least partially wrapped around a self-expanding material. 
     
     
         44 . The vascular remodeling device of  claim 38 , wherein at least one of the filaments comprises a self-expanding material with a radiopaque core or a radiopaque coating. 
     
     
         45 . The vascular remodeling device of  claim 38 , wherein a proximal porosity distally increases between the proximal ends and the equator and wherein a distal porosity distally decreases between the equator and the distal ends. 
     
     
         46 . A system comprising:
 a catheter;   a delivery lead; and   the vascular remodeling device of  claim 38 , the vascular remodeling device being detachably connected to the delivery lead and housed within the catheter.