US2016106703A1PendingUtilityA1

Fumagillol type compounds and methods of making and using same

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Assignee: ZAFGEN INCPriority: Jan 8, 2010Filed: May 21, 2015Published: Apr 21, 2016
Est. expiryJan 8, 2030(~3.5 yrs left)· nominal 20-yr term from priority
Inventors:James E. Vath
A61P 43/00A61P 3/10A61P 9/00C07D 407/04C07D 303/16A61K 9/0019A61K 31/336A61K 9/0021A61P 3/04
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Claims

Abstract

The disclosure provides a fumagillol type compound and their use in treating medical disorders, such as obesity. Pharmaceutical compositions and methods of using, e.g. in the treatment of obesity are provided.

Claims

exact text as granted — not AI-modified
What is claimed is: 
     
         1 . (canceled) 
     
     
         2 . A method of maintaining body weight in a patient formerly obese, comprising administering to the patient an effective amount of a compound represented by 
       
         
           
           
               
               
           
         
         or pharmaceutically acceptable salts or stereoisomers thereof. 
       
     
     
         3 . (canceled) 
     
     
         4 . The method of  claim 2 , wherein the patient is a human. 
     
     
         5 . The method of  claim 2 , wherein the patient has a body mass index greater than or equal to about 25 kg/m 2  before the administration. 
     
     
         6 . The method of  claim 2 , wherein the compound is administered orally, intravenously, or subcutaneously. 
     
     
         7 .- 10 . (canceled)

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