US2016106697A1PendingUtilityA1
Methods for making retinoids and uses thereof
Est. expiryAug 24, 2024(expired)· nominal 20-yr term from priority
Inventors:Wayne J. BrouilletteDonald D. MuccioVenkatram Reddy AtigaddaJohn M. RuppertSusan M. Lobo Ruppert
C07C 45/68C07C 45/513C07C 49/683C12C 11/02C07C 29/14C07C 45/30C07C 67/343C07C 49/753A61P 35/00C07C 45/29C07C 45/673C07C 403/08C07C 2602/10C07C 49/417C07D 311/96C07C 2601/02C07C 45/292C07B 2200/09C07C 47/238C07C 51/09C07C 49/403C07C 2601/16A61K 31/202C07C 49/603C07C 49/713C07C 45/61C07C 57/50A61K 9/0014C07C 2601/14C07C 403/20A61P 35/02A61P 3/06C07C 403/14C07C 57/26A61K 45/06A61P 35/04C07C 2602/28
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Claims
Abstract
Described herein are methods for making retinoids. Also described herein are retinoids and methods of use thereof.
Claims
exact text as granted — not AI-modified1 - 81 . (canceled)
82 . A pharmaceutical composition comprising a compound of formula:
and at least one pharmaceutically acceptable carrier.
83 . The pharmaceutical composition according to claim 82 , wherein the compound and the carrier are admixed.
84 . The pharmaceutical composition according to claim 82 , wherein the carrier is a solution.
85 . The pharmaceutical composition according to claim 84 , wherein the carrier is sterile water, saline, or a buffered solution at physiological pH.
86 . The pharmaceutical composition according to claim 82 , wherein the carrier is a thickener, a diluent, a buffer, a preservative, or a surface active agent.
87 . The pharmaceutical composition according to claim 82 , further comprising an additional active agent.
88 . The pharmaceutical composition according to claim 87 , wherein the additional active agent is an antimicrobial agent, an anti-inflammatory agent, or an anesthetic.
89 . The pharmaceutical composition according to claim 82 , wherein the composition is formulated for topical administration.
90 . The pharmaceutical composition according to claim 89 , wherein the topical administration is ophthalmically, vaginally, rectally, intranasally, or applied to the skin.
91 . The pharmaceutical composition according to claim 90 , wherein the topical administration is applied to the skin.
92 . The pharmaceutical composition according to claim 82 , wherein the composition is an aqueous or non-aqueous solution, suspension, or emulsion.
93 . The pharmaceutical composition according to claim 89 , wherein the formulation is an ointment, a lotion, a cream, a gel, a drop, a suppository, a spray, a liquid, or a powder.Join the waitlist — get patent alerts
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