US2016102047A1PendingUtilityA1
Substituted n-pentanamide compounds, preparation method and the use thereof
Assignee: SHANGHAI INST MATERIA MEDICAPriority: Jan 31, 2011Filed: Dec 18, 2015Published: Apr 14, 2016
Est. expiryJan 31, 2031(~4.5 yrs left)· nominal 20-yr term from priority
C07C 59/68C07C 59/64C07C 235/34C07D 263/26C07C 43/225C07C 43/23C07C 215/54C07C 217/62C07C 309/66C07C 309/73C07B 2200/07C07C 17/16C07D 263/52C07C 41/26Y02P20/582C07C 213/02C07C 309/75
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Claims
Abstract
The present invention relates to a (2R,3R)-3-(3-substituted phenyl)-2-methyl n-pentanamide compounds as shown in the formula I and the preparation method thereof, wherein, the substituents are as defined in the specification, the present invention further relates to a use of the above compounds for the preparation of tapentadol II or its pharmaceutically acceptable salt, and the intermediates involved in the preparation process
Claims
exact text as granted — not AI-modified1 - 23 . (canceled)
24 . A compound represented by any one of the follows:
wherein R is a protecting group of the phenolic hydroxyl.Join the waitlist — get patent alerts
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