US2016096890A1PendingUtilityA1

B7-h1, a novel immunoregulatory molecule

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Assignee: MAYO FOUNDATIONPriority: Nov 30, 1999Filed: Sep 3, 2015Published: Apr 7, 2016
Est. expiryNov 30, 2019(expired)· nominal 20-yr term from priority
Inventors:Lieping Chen
A61K 39/39A61K 38/00C07K 2317/526A61K 2035/124C07K 16/2827G01N 2333/70532C07K 14/70532C07K 2317/24C07K 2319/74C07K 2317/76C07K 14/47G01N 33/502G01N 33/505C07K 2317/524C07K 16/00
66
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Claims

Abstract

The invention provides novel polypeptides useful for co-stimulating T cells, isolated nucleic acid molecules encoding them, vectors containing the nucleic acid molecules, and cells containing the vectors. Also included are methods of making and using these co-stimulatory polypeptides.

Claims

exact text as granted — not AI-modified
What is claimed is: 
     
         1 - 48 . (canceled) 
     
     
         49 . A method for inhibiting the co-stimulatory activity of hB7-H1, wherein said method comprises contacting cells with an antibody that inhibits the co-stimulatory activity of hB7-H1 under conditions wherein said antibody inhibits the co-stimulatory activity of hB7-H1, wherein said hB7-H1 comprises the amino acid sequence set forth in SEQ ID NO:1.

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