US2016074417A1PendingUtilityA1

Sr-bi as a predictor of human female infertility and responsiveness to treatment

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Assignee: UNIV JOHNS HOPKINSPriority: Dec 7, 2009Filed: Sep 9, 2015Published: Mar 17, 2016
Est. expiryDec 7, 2029(~3.4 yrs left)· nominal 20-yr term from priority
Inventors:Annabelle Rodriguez
A61P 3/10A61P 35/00A61P 3/06A61P 27/02A61K 38/00A61K 31/57C12N 2310/14C12N 15/1138C12Q 2600/156C12Q 1/6883C12Q 2600/106
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Claims

Abstract

Methods of diagnosis and treatment of diseases and disorders related to de novo synthesis of cholesterol, based on allelic variants of the scavenger receptor class B type I receptor, and kits for use therein.

Claims

exact text as granted — not AI-modified
1 - 20 . (canceled) 
     
     
         21 . A method for treating a female human subject at increased risk of low progesterone levels and/or poor fetal viability during pregnancy comprising the step of administering progesterone to the female human subject based on the detection of an A allele at rs4238001 SNP in genomic DNA isolated from a biological sample obtained from the female human subject.

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