US2016067296A1PendingUtilityA1

Compositions and Methods for Joint Health

47
Assignee: UNIGEN INCPriority: Jun 17, 2013Filed: Sep 14, 2015Published: Mar 10, 2016
Est. expiryJun 17, 2033(~6.9 yrs left)· nominal 20-yr term from priority
Inventors:Lidia Alfaro BrownellMin ChuMei Feng HongEu-Jin HyunQi JiaPing JiaoYoung-Chul LeeMesfin Yimam
A61P 19/00A61P 19/02A61K 36/48A61K 31/7008A61K 36/605A61K 36/534A61K 31/353A61K 31/7034A61K 31/7028A61K 31/352A61K 31/05A61K 2300/00A61K 31/7048
47
PatentIndex Score
0
Cited by
0
References
0
Claims

Abstract

The present disclosure provides mixtures of prenylated flavonoids, stilbenes, or both with flavans or curcuminoids or both capable of modulating joint inflammation, joint pain, joint stiffness, cartilage degradation, or improving mobility, range of motion, flexibility, joint physical function, or any combination thereof. Such a mixture of prenylated flavonoids, stilbenes, or both with flavans or curcuminoids or both can optionally be used in combination with other joint management agents, such as non-steroidal anti-inflammatory agents/analgesics, COX/LOX inhibiting agents, glucosamine compounds, neuropathic pain relief agents, or the like.

Claims

exact text as granted — not AI-modified
1 - 65 . (canceled) 
     
     
         66 . A composition for joint health comprising a mixture of a  Morus  extract and an  Acacia  extract. 
     
     
         67 . The composition of  claim 66 , wherein the  Morus  extract is enriched for one or more prenylated flavonoids, one or more stilbenes or a combination thereof. 
     
     
         68 . The composition of  claim 66 , wherein the  Acacia  extract is enriched for flavans. 
     
     
         69 . The composition of  claim 66 , wherein the  Morus  extract is enriched for one or more prenylated flavonoids, one or more stilbenes or a combination thereof and wherein the  Acacia  extract is enriched for flavans. 
     
     
         70 . The composition of  claim 66 , wherein the  Morus  extract and the  Acacia  extract are blended in a 2:1 weight ratio. 
     
     
         71 . The composition of  claim 66 , wherein the  Morus  extract is from  Morus alba , and the  Acacia  extract is from  Acacia catechu.    
     
     
         72 . The composition of  claim 68 , wherein the  Acacia  extract comprises about 0.01% to 99.9% of flavans. 
     
     
         73 . The composition of  claim 67 , wherein the  Morus  extract comprises about 0.1% to 49.9% of prenylated flavonoids. 
     
     
         74 . The composition of  claim 67 , wherein the  Morus  extract comprises about 0.1% to about 49.9% of stilbenes. 
     
     
         75 . The composition of  claim 67 , wherein the one or more prenylated flavonoids comprises Albanin G, Kuwanon G, Morusin, or any combination thereof. 
     
     
         76 . The composition of  claim 67 , wherein the one or more stilbenes comprises oxyresveratrol, mulberroside A, or a combination thereof. 
     
     
         77 . The composition of  claim 66 , wherein the active ingredients in the  Acacia  extract are catechin, epicatechin, or a combination thereof. 
     
     
         78 . The composition of  claim 66 , wherein the composition additionally comprises a glucosamine-type compound. 
     
     
         79 . The composition of  claim 78 , wherein the glucosamine-type compound comprises glucosamine sulfate, glucosamine hydrochloride, N-acetylglucosamine, chondroitin sulfate, methylsulfonylmethane, hyaluronic acid or a combination thereof. 
     
     
         80 . The composition of  claim 78 , wherein the glucosamine-type compound consists essentially of glucosamine sulfate, glucosamine hydrochloride, N-acetylglucosamine, chondroitin sulfate, methylsulfonylmethane, hyaluronic acid or a combination thereof. 
     
     
         81 . The composition of  claim 66 , wherein the composition further comprises a pharmaceutically or nutraceutically acceptable carrier, diluent, or excipient, wherein the pharmaceutical or nutraceutical formulation comprises from about 0.5 weight percent to about 90 weight percent of active ingredients of the extract mixture. 
     
     
         82 . The composition of  claim 81 , wherein the composition is formulated as a tablet, hard capsule, soft gel capsule, powder, or granule. 
     
     
         83 . The composition of  claim 69 , wherein the  Morus  extract and the  Acacia  extract are blended in a 2:1 weight ratio. 
     
     
         84 . The composition of  claim 69 , wherein the composition further comprises a pharmaceutically or nutraceutically acceptable carrier, diluent, or excipient, wherein the pharmaceutical or nutraceutical formulation comprises from about 0.5 weight percent to about 90 weight percent of active ingredients of the extract mixture. 
     
     
         85 . The composition of  claim 69 , wherein the composition is formulated as a tablet, hard capsule, soft gel capsule, powder, or granule.

Join the waitlist — get patent alerts

Track US2016067296A1 — get alerts on status changes and closely related new filings.

We store only your email — no account needed. See our privacy policy.