Systems and Methods for Determining a C-Peptide Receptor, C-Peptide Receptor, and Methods of Using Same

Abstract

Systems and methods for the determination of a peptide receptor and use of it to provide a therapeutic C-peptide sensitizer. Specifically to determine a receptor for any peptide provided that the receptor is a G protein coupled receptor (GPCR).

1 . A method for C-peptide therapy comprising:
 for a particular patient, screening a plurality of different biological matters expected to be responsive to C-peptide for G protein coupled receptor (GPCR) expression;   identifying an expressed GPCR which is produced in majority of said plurality of biological matters responsive to C-peptide treatment; and   testing said GPCR for responsiveness, if it is responsive, then
 selecting a C-peptide sensitizer based on the GPCR identified; and 
 supplying a therapeutic amount of said C-peptide sensitizer along with C-peptide to said patient. 
   
     
     
         2 . The method of  claim 1  wherein said GPCR is GPR19. 
     
     
         3 . The method of  claim 1  wherein said GPCR is GPR146. 
     
     
         4 . The method of  claim 4  wherein C-peptide sensitizer is anti-GPR146ex.