Composition as auxiliary means for oral medication

Abstract

The invention relates in one aspect to acomposition, specifically a jelly, the use of which composition as an auxiliary means is to ease the taking of oral medication in solid form, which composition comprises iota-carrageenan as a jellifying agent and citric acid as a salivating agent, characterized in that the composition further comprises maltodextrin. In another aspect, the composition comprises a calcium sequestrant for adjusting Ca-ion activity of the composition. In one embodiment, the composition comprises iota-carrageenan in 0.7-1.0% in mass, citric acid in 0.06-0.07% in mass, maltodextrin in 1.5% in mass, all relative to the total mass of the composition, and an amount of a calcium sequestrant such that the Ca-ion activity of the composition is between 20 ppm and 80 ppm.

1 .- 26 . (canceled) 
     
     
         27 . A composition in the form of a jelly, comprising iota-carrageenan, citric acid and maltodextrin, wherein the amount of maltodextrin in the composition is in the range of 0.5-2.0% in mass of the total mass of the composition, wherein the composition has a yield stress of 15 Pa or higher at 20° C. as measured using a Brookfield DX3TRVT rheometer that makes use of a controlled-stress ramp to gradually increase the amount of force on the sample until flow is initiated. 
     
     
         28 . A composition according to  claim 27 , wherein the composition has a yield stress in the range of 35-50 Pa at 20° C. as measured using a Brookfield DX3TRVT rheometer that makes use of a controlled-stress ramp to gradually increase the amount of force on the sample until flow is initiated. 
     
     
         29 . A composition according to  claim 27 , wherein the amount of maltodextrin in the composition is 1.3-1.8% in mass, preferably 1.5% in mass, of the total mass of the composition. 
     
     
         30 . A composition according to  claim 27 , wherein the composition comprises citric acid in 0.05 to 0.10% in mass, preferably 0.06% in mass, of the total mass of the composition. 
     
     
         31 . A composition according to  claim 27 , wherein the amount of citric acid comprised in the composition is such that the pH of the composition lies in the range of 4.8 to 6.5 and is preferably 5.5. 
     
     
         32 . A composition according to  claim 27 , wherein the composition further comprises a calcium sequestrant for adjusting Ca-ion activity of the composition in an amount such that the Ca-ion activity of the composition is <500 ppm, preferably between 10 ppm and 100 ppm, and most preferably between 20 ppm and 80 ppm. 
     
     
         33 . A composition according to  claim 32 , wherein the calcium sequestrant comprised in the composition is calcium chloride. 
     
     
         34 . A composition according to  claim 32 , wherein the sequestrant comprised in the composition is calcium carbonate. 
     
     
         35 . A composition according to  claim 33 , wherein the amount of calcium chloride comprised in the composition is lower than 0.4% in mass, preferably 0.005-0.015% in mass, relative to the total mass of the composition. 
     
     
         36 . A composition according to  claim 27 , wherein the iota-carrageenan is comprised in an amount of 0.5 to 2% in mass, preferably 0.7 to 1.0% in mass, of the total mass of the composition. 
     
     
         37 . A composition according to  claim 27 , wherein the composition comprises water in an amount of 80-99% in mass, preferably 84-97% in mass, of the total mass of the composition. 
     
     
         38 . A composition according to  claim 27 , wherein it comprises a flavouring agent that provides one of the following flavours: orange, lemon, lime, red fruit and mint. 
     
     
         39 . A composition according to  claim 27 , wherein the composition comprises a sweetening agent chosen from the group of: saccharose, aspartame, sucralose, stevia and inuline. 
     
     
         40 . A composition according to  claim 27 , wherein the absence of hydroxypropyl methylcellulose, gelatin, spilanthol, jambu oleoresin, agar, carob, carboxy methylcellulose or xanthan gum. 
     
     
         41 . A composition according to  claim 27 , comprising 0.8% iota-carrageenan, 0.06-0.07% citric acid, 1.5% maltodextrin and 0.005% calcium chloride, all percentages in mass relative to the total mass of the composition. 
     
     
         42 . A composition according to  claim 27 , in the form of a jelly, comprising iota-carrageenan, citric acid and maltodextrin and 0.005-0.4% in mass, preferably 0.005-0.015% in mass, of calcium chloride relative to the total mass of the composition. 
     
     
         43 . A composition according to  claim 27  for coating solid-form oral medication.