US2016033539A1PendingUtilityA1

System and method of component analysis and automatic analysis device using same

Assignee: SHENZHEN MINDRAY BIO MED ELECTPriority: Apr 16, 2013Filed: Oct 16, 2015Published: Feb 4, 2016
Est. expiryApr 16, 2033(~6.7 yrs left)· nominal 20-yr term from priority
G01N 35/02G01N 2035/00356G01N 35/0092G01N 35/00584G01N 35/025
54
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Claims

Abstract

A component analysis method of an automatic analysis device is provided. The automatic analysis device includes an incubation unit that holds at least one reaction container and a plurality of executing stations set around the incubation unit to correspondingly perform a plurality of analysis operations to the reaction container. The component analysis method sets a transport period of the incubation and a chronological sequence of the analysis operations, controls the incubation unit to transport the reaction container a first transport distance during the regular transport sub-period and transport the reaction container a second transport in the self-adaptive transport sub-period, and performs at least one regular operation to the reaction container in the regular transport sub-period and at least one self-adaptive operation to reaction container in the

Claims

exact text as granted — not AI-modified
What is claimed is: 
     
         1 . A component analysis method of an automatic analysis device, the automatic analysis device comprising an incubation unit that holds at least one reaction container which contains a sample and a plurality of executing stations set around the incubation unit to correspondingly perform a plurality of analysis operations to the reaction container, the analysis method comprising:
 setting a transport period of the incubation unit and a chronological sequence of the analysis operations according to a target component to be analyzed out from the sample, wherein the transport period comprises at least one regular transport sub-period and at least one self-adaptive transport sub-period and the analysis operations comprise a plurality of regular operations and a plurality of self-adaptive operations;   controlling the incubation unit to transport the reaction container a first transport distance during the regular transport sub-period, wherein the reaction container is transported to one of the plurality of executing stations, the reaction container is performed the regular operation at the one executing station during the regular transport sub-period;   performing at least one of the regular operations to the reaction container if the chronological sequence of the regular operation matches with the regular transport sub-period;   controlling the incubation unit to transport the reaction container a second transport distance during the self-adaptive transport period, wherein the reaction container is transported to another one of the plurality of executing stations, where the reaction container is performed the self-adaptive operation during the self-adaptive transport sub-period; and   performing at least one of the self-adaptive operations to the reaction container if the chronological sequence of the self-adaptive operation matches with the self-adaptive transport sub-period;   wherein the first transport distance is calculated as a distance difference between a present position of the reaction container and a regular resting position of the reaction container in the forthcoming regular transport period, the regular resting position of the reaction container in the forthcoming regular transport period is calculated by adding a regular resting position of the reaction container in the last regular transport period with a transport interval, the transport interval is a predetermined constant distance difference defined between two regular resting positions of the same reaction container in two adjacent regular transport periods, and the second transport distance is calculated as a distance difference between the present position of the reaction container and a position of the executing station where the self-adaptive operation is performed during the forthcoming self-adaptive transport period.   
     
     
         2 . The component analysis method of  claim 1 , wherein the setting of the transport period and the analysis operations comprises generating an operation time sheet that determines which analysis operation is employed in the regular transport sub-period and the self-adaptive transport sub-period, the operation time sheet is defined as a corresponding relation between the chronological sequence of analysis operations and the transport period. 
     
     
         3 . The component analysis method of  claim 2 , wherein the regular transport sub-period comprises a regular transport duration and a regular stop duration, the incubation unit transports the reaction container the first transport distance in the regular transport duration and remains stationary in the regular stop duration, and the regular operation performed during the regular stop duration is determined by checking the operation time sheet to find whether there is the chronological sequence of at least one regular operation matches with the regular stop duration. 
     
     
         4 . The component analysis method of  claim 2 , wherein the self-adaptive transport sub-period comprises a self-adaptive transport duration and a self-adaptive stop duration, the incubation unit transports the reaction container the second transport distance in the self-adaptive transport duration and remains stationary in the self-adaptive stop duration, and the self-adaptive operation performed during the self-adaptive stop duration is determined by checking the operation time sheet to find whether there is the chronological sequence of at least one self-adaptive operation matches with the self-adaptive stop duration. 
     
     
         5 . The component analysis method of  claim 1 , wherein the transport interval is calculated by an integral multiple of a separation distance between two adjacent reaction containers on the incubation unit, the transport interval is less than a total number of the reaction containers set on the incubation unit multiples the separation distance and cannot be exact divided by the total number of the reaction containers. 
     
     
         6 . The component analysis method of  claim 1 , wherein the transport period comprise two regular transport sub-periods, the incubation unit transports the same first transport distances in these two regular transport sub-periods or the incubation unit correspondingly transports two different first transport distances in these two regular transport sub-periods. 
     
     
         7 . A component analysis method of an automatic analysis device, the automatic analysis device comprising an incubation unit that holds at least one reaction container which contains a sample and a plurality of executing stations set around the incubation unit to correspondingly perform a plurality of analysis operations to the reaction container, the component analysis method comprising:
 setting a transport period of the incubation unit and a chronological sequence of the analysis operations according to a target component to be analyzed out from the sample, wherein the transport period comprises at least one regular transport sub-period and at least one self-adaptive transport sub-period, and the analysis operations comprise a plurality of regular operations and a plurality of self-adaptive operations;   controlling the incubation unit to transport the reaction container a first transport distance during the regular transport period, wherein the reaction container is transported to one of the plurality of executing stations, the reaction container is performed the regular operation at the one executing station in the regular transport sub-period;   performing at least one of the regular operations to the reaction container if the chronological sequence of the regular operation matches with the regular transport sub-period;   controlling the incubation unit to transport the reaction container a second transport distance during the self-adaptive transport period, wherein the reaction container is transported to another one of the plurality of executing stations, where the reaction container is performed the self-adaptive operation in the self-adaptive transport sub-period;   performing at least one of the self-adaptive operations to the reaction container if the chronological sequence of the self-adaptive operation matches with the self-adaptive transport sub-period; and   controlling the incubation unit to return to a regular resting position where the incubation unit stays in the last regular transport sub-period after the present self-adaptive operation is finish;   wherein the first transport distance is a predetermined constant distance difference, and the second transport distance is calculated as a distance difference between the present position of the reaction container and a position of the executing station where the self-adaptive operation is performed during the forthcoming self-adaptive transport period.   
     
     
         8 . The component analysis method of  claim 7 , wherein the first transport distance is calculated by an integral multiple of a separation distance between two adjacent reaction containers on the incubation unit, the transport interval is less than a total number of the reaction containers set on the incubation unit multiples the separation distance and cannot be exact divided by the total number of the reaction containers. 
     
     
         9 . An analysis system of an automatic analysis device, the automatic analysis device comprising an incubation unit that holds at least one reaction container which contains a sample and an operation mechanism set around the incubation unit to perform a plurality of analysis operations to the reaction container, the analysis system comprising:
 a transport control unit that controls the incubation unit to transport the reaction container in accordance with a preset transport period, wherein the transport period comprises at least one regular transport sub-period and at least one self-adaptive transport sub-period, the analysis operations comprises a plurality of regular operation and a plurality of self-adaptive operation;   a regular operation control unit that controls the operation mechanism to perform at least one of the regular operations to the reaction container in the regular transport sub-period if a chronological sequence of the regular operation matches with the regular transport sub-period; and   a self-adaptive operation control unit that controls the operation mechanism to perform the self-adaptive operation to the reaction container during the self-adaptive transport sub-period if a chronological sequence of the self-adaptive operation matches with the self-adaptive transport sub-period;   wherein the incubation unit is controlled to transport the first transport distance in the regular transport sub-period, the first transport distance is calculated as a distance difference between a present position of the reaction container and a regular resting position of the reaction container in the forthcoming regular transport period, the regular resting position of the reaction container in the forthcoming regular transport period is calculated by adding a regular resting position of the reaction container in the last regular transport period with a transport interval, the transport interval is a predetermined constant distance difference defined between two regular resting positions of the same reaction container in two adjacent regular transport periods, the incubation unit is controlled to transport a second transport distance in the self-adaptive transport sub-period, and the second transport distance is calculated as a distance difference between the present position of the reaction container and a position of an executing station where the self-adaptive operation is performed during the forthcoming self-adaptive transport period.   
     
     
         10 . The analysis system of  claim 9 , further comprising an operation time sheet generating unit that generates an operation time sheet that determines which analysis operation is employed in the regular transport sub-period and the self-adaptive transport sub-period, wherein the operation time sheet is defined as a corresponding relation between the chronological sequence of analysis operations and the transport period. 
     
     
         11 . The analysis system of  claim 10 , wherein the regular transport sub-period comprises a regular transport duration and a regular stop duration, the transport control unit controls the incubation unit transports the reaction container the first transport distance in the regular transport duration and remains stationary in the regular stop duration, and the regular operation control unit determines the regular operation performed during the regular stop duration by checking the operation time sheet to find whether there is the chronological sequence of at least one regular operation matches with the regular stop duration. 
     
     
         12 . The analysis system of  claim 10 , wherein the self-adaptive transport sub-period comprises a self-adaptive transport duration and a self-adaptive stop duration, the transport control unit controls the incubation unit transports the reaction container the second transport distance in the self-adaptive transport duration and remains stationary in the self-adaptive stop duration, and the self-adaptive operation control unit determines the self-adaptive operation performed during the self-adaptive stop duration by checking the operation time sheet to find whether there is the chronological sequence of at least one self-adaptive operation matches with the self-adaptive stop duration. 
     
     
         13 . An analysis system of an automatic analysis device, the automatic analysis device comprising an incubation unit that holds at least one reaction container which contains a sample and an operation mechanism set around the incubation unit to perform a plurality of analysis operations to the reaction container, the analysis system comprising:
 a transport control unit that controls the incubation unit to transport the reaction container in accordance with a preset transport period, wherein the transport period comprises at least one regular transport sub-period and at least one self-adaptive transport sub-period, the analysis operations comprises a plurality of regular operation and a plurality of self-adaptive operation;   a regular operation control unit that controls the operation mechanism to perform at least one of the regular operations to the reaction container in the regular transport sub-period if a chronological sequence of the regular operation matches with the regular transport sub-period; and   a self-adaptive operation control unit that controls the operation mechanism to perform the self-adaptive operation to the reaction container in the self-adaptive transport sub-period if a chronological sequence of the self-adaptive operation matches with the self-adaptive transport sub-period;   wherein the incubation unit is controlled to transport the first transport distance in the regular transport sub-period, the first transport distance is a predetermined constant distance difference, the second transport distance is calculated as a distance difference between the present position of the reaction container and a position of an executing station where the self-adaptive operation is performed during the forthcoming self-adaptive transport period, and the transport control unit controls the incubation unit to return to a regular resting position where the incubation unit stays in the last regular transport sub-period after the present self-adaptive operation is finish.   
     
     
         14 . An automatic analysis device for analyzing a target component in a sample, comprising:
 an incubation unit comprising at least one container holders that holds a reaction container which contains the sample;   an operation mechanism set around the incubation unit and performs a plurality of analysis operations to the reaction container;   a plurality of executing stations defined at an intersection of the container holder and a movement track or a center line of the operation mechanism;   a processor; and   a non-transitory computer readable medium storing instructions to cause the processor to:
 set a transport period of the incubation unit and a chronological sequence of the analysis operations according to a target component to be analyzed out from the sample, wherein the transport period comprises at least one regular transport sub-period and at least one self-adaptive transport sub-period and the analysis operations comprise a plurality of regular operation and a plurality of self-adaptive operation; 
 control the incubation unit to transport the reaction container a first transport distance during the regular transport period, wherein the reaction container is transported to one of the plurality of executing stations, where the reaction container is performed the regular operation during the regular transport sub-period; 
 control the operation mechanism to perform at least one of the regular operations to the reaction container if the chronological sequence of the regular operation matches with the regular transport sub-period; 
 control the incubation unit to transport the reaction container a second transport distance during the self-adaptive transport period, wherein the reaction container is transported to another one of the plurality of executing station, where the reaction container is performed the self-adaptive operation in the self-adaptive transport duration; and 
 control the operation mechanism to perform at least one of the self-adaptive operation to the reaction container if the chronological sequence of the self-adaptive operation matches with the self-adaptive transport sub-period; 
   wherein the first transport distance is calculated as a distance difference between a present position of the reaction container and a regular resting position of the reaction container in the forthcoming regular transport period, the regular resting position of the reaction container in the forthcoming regular transport period is calculated by adding a regular resting position of the reaction container in the last regular transport period with a transport interval, the transport interval is a predetermined constant distance difference defined between two regular resting positions of the same reaction container in two adjacent regular transport periods, and the second transport distance is calculated as a distance difference between the present position of the reaction container and a position of the executing station where the self-adaptive operation is performed during the forthcoming self-adaptive transport period.   
     
     
         15 . The automatic analysis device of  claim 14 , further storing instruction to cause the processor to:
 generate an operation time sheet that determines which analysis operation is employed in the regular transport sub-period and the self-adaptive transport sub-period;   wherein the operation time sheet is defined as a corresponding relation between the chronological sequence of analysis operations and the transport period.   
     
     
         16 . The automatic analysis device of  claim 15 , wherein the regular transport sub-period comprises a regular transport duration and a regular stop duration, the processor is caused to control the incubation unit to transport the reaction container the first transport distance during the regular transport duration and remain stationary in the regular stop duration, and the regular operation performed during the regular stop duration is determined by checking the operation time sheet to find whether there is the chronological sequence of at least one regular operation matches with the regular stop duration. 
     
     
         17 . The automatic analysis device of  claim 15 , wherein the self-adaptive transport sub-period comprises a self-adaptive transport duration and a self-adaptive stop duration, the processor is caused to control the incubation unit to transport the reaction container the second transport distance during the self-adaptive transport duration and remains stationary in the self-adaptive stop duration, and the self-adaptive operation performed during the self-adaptive stop duration is determined by checking the operation time sheet to find whether there is the chronological sequence of at least one self-adaptive operation matches with the self-adaptive stop duration. 
     
     
         18 . The automatic analysis device of  claim 14 , wherein the transport interval is calculated by an integral multiple of a separation distance between two adjacent reaction containers on the incubation unit, the transport interval is less than a total number of the reaction containers set on the incubation unit multiples the separation distance and cannot be exact divided by the total number of the reaction containers. 
     
     
         19 . The automatic analysis device of  claim 14 , wherein the regular operations are defined as the analysis operations requiring no incubation in advance, and the regular operations comprise a move-in operation to move the reaction container on the incubation unit and a photometry operation to detect a luminous intensity of the target component in the sample. 
     
     
         20 . The automatic analysis device of  claim 14 , wherein the self-adaptive operations are defined as the analysis operations requiring incubation in advance, and the self-adaptive operations comprise a move-out operation to move the reaction container out of the incubation unit and a reagent injecting operation to add a reagent second time in the sample.

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