US2016030402A1PendingUtilityA1

Sustained-release nanoparticle compositions and methods for using the same

Assignee: UNIV NEBRASKA BY AND BEHALF OF THE UNIVERSITY OF NEBRASKA MEDICAL BOARD OF REGENTSPriority: Dec 21, 2004Filed: Sep 21, 2015Published: Feb 4, 2016

Est. expiryDec 21, 2024(expired)· nominal 20-yr term from priority

Inventors:Vinod Labhasetwar Sanjeeb Kumar Sahoo Maram K. Reddy

A61P 37/00A61P 9/00A61P 29/00A61P 31/00A61P 35/00A61K 9/5138Y10S977/906A61K 9/5192A61K 31/337A61K 9/4816Y10S977/773A61K 9/1641A61K 31/00A61K 9/1635A61K 31/436A61K 9/5146A61K 9/5026A61K 9/0019B82Y 5/00A61P 17/00

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Claims

Abstract

The present invention is a composition composed of a therapeutic agent encapsulated in a copolymer of an N-alkylacrylamide, a vinyl monomer, and a polyethylene glycol (PEG) conjugate and a method for using the same in the treatment or prevention of a disease or condition.

Claims

exact text as granted — not AI-modified

What is claimed is: 
     
         1 . A sustained-release nanoparticle composition comprising a copolymer of an N-alkylacrylamide, a vinyl monomer, and a polyethylene glycol conjugate. 
     
     
         2 . The sustained-release nanoparticle composition of  claim 1 , further comprising a therapeutic agent. 
     
     
         3 . A method for preventing or treating a disease or condition comprising locally administering to a patient having or at risk of having a disease or condition, an effective amount of a composition of  claim 2  thereby preventing or treating the disease or condition in the patient.

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