Fluorescent probe

Abstract

A compound represented by the formula (I) (R 1 represents hydrogen atom or a monovalent substituent; R 2 and R 3 represent hydrogen atom, an alkyl group, or a halogen atom; R 4 and R 5 represent an alkyl group or an aryl group; R 6 and R 7 represent hydrogen atom, an alkyl group, or a halogen atom; R 8 represent hydroxy group or a dialkoxyboranetriyl group; and X represents silicon atom, germanium atom, or tin atom), which is a novel fluorophore usable as a mother nucleus of an off/on type fluorescent probe not utilizing the intramolecular photoinduced electron transfer.

What is claimed is: 
     
         1 . A compound represented by the following general formula (III): 
       
         
           
           
               
               
           
         
       
       wherein, in the formula, R 2  and R 3  independently represent hydrogen atom, an alkyl group having 1 to 6 carbon atoms, or a halogen atom; R 6  and R 7  independently represent hydrogen atom, an alkyl group having 1 to 6 carbon atoms, or a halogen atom; and R 12  represents a halogen atom, or a salt thereof. 
     
     
         2 . An N,N,N′,N′-tetrallyl-diamino-X-xanthone compound represented by the following formula: 
       
         
           
           
               
               
           
         
       
       wherein, in the formula, R 2  and R 3  independently represent hydrogen atom, an alkyl group having 1 to 6 carbon atoms, or a halogen atom; R 4  and R 5  independently represent an alkyl group having 1 to 6 carbon atoms, or an aryl group having 1 to 6 carbon atoms; R 6  and R 7  independently represent hydrogen atom, an alkyl group having 1 to 6 carbon atoms, or a halogen atom; and X represents silicon atom, germanium atom, or tin atom, or a salt thereof. 
     
     
         3 . A diamino-X-xanthone compound represented by the following formula: 
       
         
           
           
               
               
           
         
       
       wherein, in the formula, 
       R 2  and R 3  independently represent hydrogen atom, an alkyl group having 1 to 6 carbon atoms, or a halogen atom; R 4  and R 5  independently represent an alkyl group having 1 to 6 carbon atoms, or an aryl group having 1 to 6 carbon atoms; R 6  and R 7  independently represent hydrogen atom, an alkyl group having 1 to 6 carbon atoms, or a halogen atom; and X represents silicon atom, germanium atom, or tin atom, or a salt thereof. 
     
     
         4 . A dihydroxy-X-xanthone compound represented by the following formula: 
       
         
           
           
               
               
           
         
       
       wherein, in the formula, R 2  and R 3  independently represent hydrogen atom, an alkyl group having 1 to 6 carbon atoms, or a halogen atom; R 4  and R 5  independently represent an alkyl group having 1 to 6 carbon atoms, or an aryl group having 1 to 6 carbon atoms; R 6  and R 7  independently represent hydrogen atom, an alkyl group having 1 to 6 carbon atoms, or a halogen atom; and X represents silicon atom, germanium atom, or tin atom, or a salt thereof. 
     
     
         5 . A compound represented by the following general formula (IV): 
       
         
           
           
               
               
           
         
       
       wherein, in the formula, R 2  and R 3  independently represent hydrogen atom, an alkyl group having 1 to 6 carbon atoms, or a halogen atom; R 4  and R 5  independently represent an alkyl group having 1 to 6 carbon atoms, or an aryl group having 1 to 6 carbon atoms; R 6  and R 7  independently represent hydrogen atom, an alkyl group having 1 to 6 carbon atoms, or a halogen atom; R 13  represents a protective group of phenolic hydroxy group; and X represents silicon atom, germanium atom, or tin atom, or a salt thereof.