Interface Devices, Systems, And Methods For Use With Intravascular Pressure Monitoring Devices

Abstract

Embodiments of the present disclosure are configured to assess the severity of a blockage in a vessel and, in particular, a stenosis in a blood vessel. In some particular embodiments, the devices, systems, and methods of the present disclosure are configured to provide FFR measurements over a length of a vessel of interest in a small, compact device that integrates with existing proximal and distal pressure measurement systems and does not require a separate power source.

What is claimed is: 
     
         1 . An interface for intravascular pressure sensing devices, comprising:
 a distal input configured to receive a distal pressure signal from a distal pressure sensing device;   a proximal input configured to receive a proximal pressure signal from a proximal pressure sensing device;   a pullback device configured to interface with a proximal portion of the distal pressure sensing device to cause translation of the distal pressure sensing device relative to the proximal pressure sensing device;   a processor in communication with the distal input, proximal input, and the pullback device, the processor configured to calculate a pressure differential between the distal pressure and the proximal pressure based on the received distal pressure signal and the received proximal pressure signal obtained as the pullback device translates the distal pressure sensing device relative to the proximal pressure sensing device; and   a display in communication with the processor and configured to display the pressure differential calculated by the processor including a relative position of the distal pressure sensing device to the proximal pressure sensing device associated with the calculated pressure differential.   
     
     
         2 . The interface of  claim 1 , further comprising:
 a distal output configured to output the distal pressure signal to a hemodynamic system in a format useable by the hemodynamic system;   a proximal output configured to output the proximal pressure signal to the hemodynamic system in a format useable by the hemodynamic system;   
     
     
         3 . The interface of  claim 2 , wherein the distal input, distal output, proximal input, proximal output, and processor are secured to a housing. 
     
     
         4 . The interface of  claim 3 , wherein the housing has a width between 5 cm and 25 cm, a height between 5 cm and 25 cm, and a depth between 1 cm and 10 cm. 
     
     
         5 . The interface of  claim 1 , herein the distal pressure sensing device is a pressure-sensing guide wire. 
     
     
         6 . The interface of  claim 5 , wherein the proximal pressure sensing device is a pressure-sensing catheter. 
     
     
         7 . The interface of  claim 1 , wherein the processor is further configured to identify a diagnostic window for calculating the pressure differential, the diagnostic window consisting of a portion of a heartbeat cycle of a patient. 
     
     
         8 . The system of  claim 7 , wherein the portion of the heartbeat cycle of the patient is selected at least partially based on one or more characteristics of the proximal pressure signal. 
     
     
         9 . The system of  claim 7 , wherein the portion of the heartbeat cycle of the patient is selected at least partially based on one or more characteristics of the distal pressure signal. 
     
     
         10 . A system for evaluating a vascular stenosis, the system comprising:
 a distal pressure sensing device sized and shaped for insertion into human vasculature;   a proximal pressure sensing device sized and shaped for insertion into human vasculature; and   an interface comprising:
 a distal input configured to receive a distal pressure signal from a distal pressure sensing device; 
 a proximal input configured to receive a proximal pressure signal from a proximal pressure sensing device; 
 a pullback device configured to interface with a proximal portion of the distal pressure sensing device to cause translation of the distal pressure sensing device relative to the proximal pressure sensing device; 
 a processor in communication with the distal input, proximal input, and the pullback device, the processor configured to calculate a pressure differential between the distal pressure and the proximal pressure based on the received distal pressure signal and the received proximal pressure signal obtained as the pullback device translates the distal pressure sensing device relative to the proximal pressure sensing device; and 
   a display in communication with the processor of the interface, the display configured to display the pressure differential calculated by the processor including a relative position of the distal pressure sensing device to the proximal pressure sensing device associated with the calculated pressure differential.   
     
     
         11 . The system of  claim 10 , wherein the display is a touchscreen. 
     
     
         12 . The system of  claim 10 , wherein the display is further configured to display the proximal pressure and the distal pressure. 
     
     
         13 . The system of  claim 10 , wherein the interface further comprises a distal output configured to output the distal pressure signal to a processing system in a format useable by the processing system. 
     
     
         14 . The system of  claim 13 , wherein the processing system is a hemodynamic system. 
     
     
         15 . The system of  claim 13 , wherein the distal input, distal output, proximal input, and processor are secured to a housing. 
     
     
         16 . The system  claim 10 , wherein the distal pressure sensing device is a pressure-sensing guide wire. 
     
     
         17 . The system of  claim 16 , wherein the proximal pressure sensing device is a pressure-sensing catheter. 
     
     
         18 . The system of  claim 10 , wherein the processor is farther configured to identify a diagnostic window for calculating the pressure differential, the diagnostic window consisting of a portion of a heartbeat cycle of a patient. 
     
     
         19 . The system of  claim 18 , wherein the portion of the heartbeat cycle of the patient is selected at least partially based on one or more characteristics of the proximal pressure signal. 
     
     
         20 . The system of  claim 18 , wherein the portion of the heartbeat cycle of the patient is selected at least partially based on one or more characteristics of the distal pressure signal.