US2016009794A1PendingUtilityA1

Antibody to n-terminal region of hemoglobin beta-chain

Assignee: SEKISUI MEDICAL CO LTDPriority: Dec 11, 2008Filed: Aug 5, 2015Published: Jan 14, 2016
Est. expiryDec 11, 2028(~2.4 yrs left)· nominal 20-yr term from priority
C07K 2317/14G01N 33/531C07K 2317/33C07K 14/805C07K 16/18C12N 5/163C07K 2317/34G01N 33/723G01N 33/721
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Claims

Abstract

Provided is a general-purpose technique capable of measuring the HbA1c content, which is comparable to the IFCC reference method. An antibody which reacts with a peptide or a protein having an amino acid sequence of VHLTPE (SEQ ID NO: 1) at the N-terminus in which the N-terminal valine is not modified, but does not react with a peptide or a protein in which the N-terminal valine of the relevant polypeptide or protein is modified.

Claims

exact text as granted — not AI-modified
1 . An antibody which reacts with a peptide or a protein comprising an amino acid sequence of VHLTPE (SEQ ID NO: 1) at the N-terminus in which the N-terminal valine is not modified, but does not react with a peptide or a protein comprising an amino acid sequence of VHLTPE (SEQ ID NO: 1) at the N-terminus in which the N-terminal valine is modified.

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