US2016007917A1PendingUtilityA1
System and method for diagnosing a fluid status of a patient
Est. expiryMay 18, 2025(expired)· nominal 20-yr term from priority
Inventors:Alejandro Ortiz-Burgos
A61B 5/0263A61B 5/02028A61B 6/03A61B 8/04A61B 5/021A61B 5/7225A61B 5/7278A61B 5/029A61B 5/7282A61B 5/4878A61B 5/7246A61B 5/412A61B 5/369A61B 8/065A61B 5/055A61B 6/503A61B 5/0044
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Claims
Abstract
A system and method for diagnosing a fluid status of a patient includes non-invasively determining a left ventricular pressure of blood within a left ventricle of a heart of the patient. The left ventricular pressure is compared to a predefined pressure value to diagnose the fluid status.
Claims
exact text as granted — not AI-modifiedI claim:
1 . A method of diagnosing a fluid status of a patient, the method comprising:
non-invasively determining a left ventricular pressure of blood within a left ventricle of a heart of the patient; and comparing the left ventricular pressure to a predefined pressure value to diagnose the fluid status.
2 . The method according to claim 1 , wherein the diagnosis of the fluid status is used to determine the health of the patient with respect to at least one of fluid amounts and fluid distributions in the body.
3 . The method according to claim 1 , wherein the diagnosis of the fluid status is used to identify the existence of at least one of dehydration, sepsis, pulmonary edema, low blood volume, and shifts in intravascular fluid volumes.
4 . The method according to claim 1 , wherein the diagnosis of the fluid status is used to determine that no fluid-related problems exist.
5 . The method according to claim 1 , wherein non-invasively determining a left ventricular pressure further comprises non-invasively measuring a plurality of cardiac parameters of the patient, including a stroke volume of the left ventricle, a mitral valve area, and a left ventricular diastolic filling time.
6 . The method according to claim 5 , wherein the cardiac parameters are measured using one of an echocardiogram apparatus, a magnetic resonance imaging (MRI) apparatus, and a computer aided tomography (CAT) apparatus.
7 . The method according to claim 1 , wherein non-invasively determining a left ventricular pressure further comprises:
non-invasively measuring a plurality of cardiac parameters of the patient, including a stroke volume of the left ventricle, a mitral valve area, and a left ventricular diastolic filling time; and calculating a left ventricular end-diastolic pressure using a formula:
L
V
E
D
P
=
36
ρ
(
SV
A
mitral
(
Δ
t
D
)
)
2
,
where LVEDP is the left ventricular end-diastolic pressure, ρ is a density of blood; SV is the stroke volume, A mitral is the mitral valve area, and Δt D is the left ventricular diastolic filling time.
8 . The method according to claim 1 , wherein non-invasively determining a left ventricular pressure further comprises:
non-invasively measuring a plurality of cardiac parameters of the patient, including a stroke volume of the left ventricle, a mitral valve area, a maximum velocity of blood entering the left ventricle, and a left ventricular diastolic filling time; and calculating a left ventricular end-diastolic pressure using a formula:
L
V
E
D
P
=
3
π
ρ
(
SV
)
v
max
A
mitral
Δ
t
D
,
where LVEDP is the left ventricular end-diastolic pressure, ρ is a density of blood; SV is the stroke volume, v max is the maximum velocity of blood, A mitral is the mitral valve area, and Δt D is the left ventricular diastolic filling time.
9 . The method according to claim 1 , wherein non-invasively determining a left ventricular pressure further comprises:
non-invasively measuring a plurality of cardiac parameters, including a volume of the left ventricle, a velocity of blood entering the left ventricle, and a mitral valve area; monitoring a change in velocity of the blood entering the left ventricle over time; and calculating the left ventricular pressure using a formula:
L
V
P
=
ρ
V
A
mitral
v
t
+
ρ
v
2
,
where LVP is the left ventricular pressure, ρ is a density of blood; V is the volume of the left ventricle, A mitral is the mitral valve area, v is the velocity of blood entering the left ventricle, and
v
t
is the change in velocity over time.
10 . A fluid status diagnostic system comprising:
a sensing unit configured to non-invasively measure a plurality of cardiac parameters associated with a left ventricle of a patient, the cardiac parameters including a mitral valve area, and at least one of a stroke volume of the left ventricle, a left ventricular diastolic filling time, a velocity of blood entering the left ventricle, a maximum velocity of blood entering the left ventricle, and a change in velocity of blood entering the left ventricle over time; and a processor configured to receive the plurality of cardiac parameters, calculate a left ventricular pressure using the measured cardiac parameters, and compare the left ventricular pressure to a predefined pressure value for assisting in the diagnosis of a fluid status.
11 . The system according to claim 10 , wherein the diagnosis of the fluid status is used to determine the health of the patient with respect to at least one of fluid amounts and fluid distributions in the body.
12 . The system according to claim 10 , wherein the diagnosis of the fluid status is used to identify the existence of at least one of dehydration, sepsis, pulmonary edema, low blood volume, and shifts in intravascular fluid volumes.
13 . The system according to claim 10 , wherein the diagnosis of the fluid status is used to determine that no fluid-related problems exist.
14 . The system according to claim 10 , wherein the cardiac parameters are measured using one of an echocardiogram apparatus, a magnetic resonance imaging (MRI) apparatus, and a computer aided tomography (CAT) apparatus.
15 . The system according to claim 10 , wherein the processor calculates the left ventricular pressure by calculating a left ventricular end-diastolic pressure using a formula:
L
V
E
D
P
=
36
ρ
(
SV
A
mitral
(
Δ
t
D
)
)
2
,
where LVEDP is the left ventricular end-diastolic pressure, p is a density of blood; SV is the stroke volume, A mitral is the mitral valve area, and Δt D is the left ventricular diastolic filling time.
16 . The system according to claim 10 , wherein the processor calculates the left ventricular pressure by calculating a left ventricular end-diastolic pressure using a formula:
L
V
E
D
P
=
3
π
ρ
(
SV
)
v
max
A
mitral
Δ
t
D
,
where LVEDP is the left ventricular end-diastolic pressure, ρ is a density of blood; SV is the stroke volume, v max is the maximum velocity of blood, A mitral is the mitral valve area, and Δt D is the left ventricular diastolic filling time.
17 . The system according to claim 10 , wherein the processor calculates the left ventricular pressure using a formula:
L
V
P
=
ρ
V
A
mitral
v
t
+
ρ
v
2
,
where LVP is the left ventricular pressure, ρ is a density of blood; V is a volume of the left ventricle, A mitral is the mitral valve area, v is the velocity of blood entering the left ventricle, and
v
t
is the change in velocity over time.Join the waitlist — get patent alerts
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