Oligosaccharide mixture and food product comrpising this mixture, especially infant formula

Abstract

The invention discloses an oligosaccharide mixture comprising 5-70 wt % of at least one N-acetylated oligosaccharide, 5-90 wt % of at least one neutral oligosaccharide, 2-50 wt % of at least one sialylated oligosaccharide, and/or 5-70 wt % of at least one fucosylated oligosaccharide. The invention also discloses a food product, especially an infant formula, comprising said oligosaccharide mixture.

The invention is claimed as follows: 
     
         1 . An oligosaccharide mixture comprising:
 5-70 wt % of at least one N-acetylated oligosaccharide selected from the group consisting of N-acetyl-galactosaminyl-lactose and galactosyl-N-acetyl-galactosaminyl-lactose;   5-90 wt % of at least one galacto-oligosaccharide selected from the group consisting of Galβ1,6Gal, Galβ1,6Galβ1,4Glc, Galβ1,6Galβ1,6Glc, Galβ1,3Galβ1,3Glc, Galβ1,3Galβ1,4Glc, Galβ1,6Galβ1,6Galβ1,4Glc, Galβ1,6Galβ1,3Galβ1,4Glc, Galβ1,3Galβ1,6Galβ1,4Glc, Galβ1,3Galβ1,3Galβ1,4Glc, Galβ1,4Galβ1,4Glc and Galβ1,4Galβ1,4Galβ1,4Glc;   2-50 wt % of at least one sialylated oligosaccharide selected from the group consisting of 3′-sialyllactose and 6′-sialyllactose; and   2-70 wt % of at least one fucosylated oligosaccharide selected from the group consisting of 2′-fucosyllactose, 3-fucosyllactose, difucosyllactose, lacto-N-fucopentaoses, lacto-N-difucohexaose I, monofucosyllacto-N-hexaose, Difucosyllacto-N-hexaose I and Difucosyllacto-N-neohexaose II.   
     
     
         2 . The oligosaccharide mixture of  claim 1 , comprising:
 5-50 wt % of the at least one N-acetylated oligosaccharide,   5-70 wt % of the at least one galacto-oligosaccharide,   2-40 wt % of the at least one sialylated oligosaccharide, and   10-70 wt % of the at least one fucosylated oligosaccharide.   
     
     
         3 . The oligosaccharide mixture of  claim 1 , comprising:
 10-40 wt % of the at least one N-acetylated oligosaccharide,   5-35 wt % of the at least one galacto-oligosaccharide,   2-20 wt % of the at least one sialylated oligosaccharide, and   30-60 wt % of the at least one fucosylated oligosaccharide.   
     
     
         4 . The oligosaccharide mixture of  claim 1 , comprising 25 wt % of the at least one N-acetylated oligosaccharide, 20 wt % of the at least one galacto-oligosaccharide, 10 wt % of the at least one sialylated oligosaccharide and 45 wt % of the at least one fucosylated oligosaccharide. 
     
     
         5 . The oligosaccharide mixture of  claim 1 , wherein the oligosaccharide mixture is a synthetic composition. 
     
     
         6 . The oligosaccharide mixture of  claim 1 , wherein the at least one sialylated oligosaccharide and/or the at least one fucosylated oligosaccharide comprises an oligosaccharide that has been obtained by a process comprising a step selected from the group consisting of isolation from a natural source, chemical synthesis, and biotechnological synthesis. 
     
     
         7 . A food product comprising:
 an oligosaccharide mixture which comprises:
 5-70 wt % of at least one N-acetylated oligosaccharide selected from the group consisting of N-acetyl-galactosaminyl-lactose and galactosyl-N-acetyl-galactosaminyl-lactose, 
 5-90 wt % of at least one galacto-oligosaccharide selected from the group consisting of Galβ1,6Gal, Galβ1,6Galβ1,4Glc, Galβ1,6Galβ1,6Glc, Galβ1,3Galβ1,3Glc, Galβ1,3Galβ1,4Glc, Galβ1,6Galβ1,6Galβ1,4Glc, Galβ1,6Galβ1,3Galβ1,4Glc, Galβ1,3Galβ1,6Galβ1,4Glc, Galβ1,3Galβ1,3Galβ1,4Glc, Galβ1,4Galβ1,4Glc and Galβ1,4Galβ1,4Galβ1,4Glc, 
 2-50 wt % of at least one sialylated oligosaccharide selected from the group consisting of 3′-sialyllactose and 6′-sialyllactose; and 
 2-70 wt % of at least one fucosylated oligosaccharide selected from the group consisting of 2′-fucosyllactose, 3-fucosyllactose, difucosyllactose, lacto-N-fucopentaoses, lacto-N-difucohexaose I, monofucosyllacto-N-hexaose, Difucosyllacto-N-hexaose I and Difucosyllacto-N-neohexaose II. 
   
     
     
         8 . The food product of  claim 7 , which is selected from the group consisting of a starter infant formula, an infant formula, a baby food, an infant cereal composition, a follow-up formula and a growing-up milk. 
     
     
         9 . The food product of  claim 7 , wherein the food product comprises at least one probiotic bacterial strain. 
     
     
         10 . The food product of  claim 7  comprising a protein source, a fat source and a carbohydrate source. 
     
     
         11 . The food product of  claim 10  wherein the carbohydrate source comprises lactose. 
     
     
         12 . The food product of  claim 10  wherein the carbohydrate source comprises at least one of saccharose, maltodextrin or starch. 
     
     
         13 . The food product of  claim 10  wherein the fat source comprises at least one of palm oleic, high oleic sunflower oil or high oleic safflower oil. 
     
     
         14 . The food product of  claim 10  wherein the fat source comprises at least one of linoleic acid, α-linolenic acid, arachidonic acid or docosahexaenoic acid. 
     
     
         15 . The food product of  claim 14  wherein the fat source has a ratio of n-6 to n-3 fatty acids of 5:1 to 15:1. 
     
     
         16 . The food product of  claim 7  comprising at least one of soy lecithin, a citric acid ester of a mono-glyceride, or a citric acid ester of a di-glyceride. 
     
     
         17 . The food product of  claim 7  comprising at least one of lactoferrin, a nucleotide, or a nucleoside.