US2015329482A1PendingUtilityA1

Preparation of 13-Cyclohexyl-3-Methoxy-6-[Methyl-(2-(2-[Methyl-(Sulphamoyl)-Amino]-Ethoxy}-Ethyl)-Carbamoyl]-7H-Indolo-{2,1-a]-[2]-Benzazepine-10-Carboxylic Acid

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Assignee: JANSSEN SCIENCES IRELAND UCPriority: Jun 24, 2010Filed: Jul 28, 2015Published: Nov 19, 2015
Est. expiryJun 24, 2030(~3.9 yrs left)· nominal 20-yr term from priority
Inventors:Tom Cornelis Hortense GovaertsJean-Pierre Andre Marc BongartzPatrick Hubert J. Nieste
C07D 223/14C07C 307/06C07D 487/04
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Claims

Abstract

The present invention relates to an improved method for the preparation of 13-cyclohexyl-3-methoxy-6-[methyl-(2-{2-[methyl-(sulphamoyl)-amino]-ethoxy}ethyl)-carbamoyl]-7H-indolo-[2,1-a]-[2]-benzazepine-10-carboxylic acid. The present invention also relates to a new compound, namely tent-butyl (methyl-{2-[2-(methylamino)-ethoxy]-ethyl}-sulphamoyl)-carbamate, used in this improved method.

Claims

exact text as granted — not AI-modified
1 .- 7 . (canceled) 
     
     
         8 . tert-Butyl (methyl-{2-[2-(methylamino)-ethoxy]-ethyl}-sulphamoyl)-carbamate, and acid-addition salts thereof.

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