Peptide

Abstract

The invention provides a peptide comprising or consisting of FSY and variants thereof, particularly comprising or consisting of the sequence FTY, nucleic acids encoding said peptides and pharmaceutical and nutraceutical compositions comprising said peptide(s) and/or nucleic acids. Also provided is the use of such a peptide in therapy and in vitro methods of ACE-inhibition.

1 - 6 . (canceled) 
     
     
         7 . An isolated peptide consisting of the sequence FSY or FTY. 
     
     
         8 . A pharmaceutical composition comprising a peptide according to  claim 7  together with a pharmaceutically acceptable excipient. 
     
     
         9 . A pharmaceutical composition comprising
 (i) an isolated peptide having ACE-inhibitory activity and consisting of the sequence FSY or FTY; and   (ii) a further anti-hypertensive agent.   
     
     
         10 . A pharmaceutical composition according to  claim 9 , wherein said further anti-hypertensive agent is a further peptide having ACE-inhibitory activity and comprising or consisting of the sequence FSY or FTY. 
     
     
         11 . A nutraceutical composition comprising a peptide according to  claim 7  together with an excipient or carrier. 
     
     
         12 . A nutraceutical composition comprising a peptide having ACE-inhibitory activity and consisting of the sequence FSY or FTY together with one or more nutraceutical components selected from fat, carbohydrates, protein, fibres, ash, minerals and vitamins. 
     
     
         13 . A food or feed comprising a peptide having ACE-inhibitory activity and consisting of the sequence FSY or FTY. 
     
     
         14 . A food or feed according to  claim 13 , wherein said food or feed is selected from instant powder products, food bars, meat and meat analogue products, fish and fish analogue products, breakfast cereals, vegetable fat spreads, mayonnaise, dairy products, soy milk products, pasta, noodles, baked goods, ready meals, infant formula, baby food, pet food, livestock feed and aquaculture feed. 
     
     
         15 - 19 . (canceled)