Wound healing device

Abstract

A plasma coating device for treating a wound comprises a plasma chamber having: one or more electrodes, a gas supply inlet, a plasma outlet exposed to ambient pressure, and an ignition system operatively connected to the electrodes for providing a non-thermal equilibrium plasma within the plasma chamber. An aerosol delivery system is operable to introduce a bioresorbable material as an aerosol into the plasma, to produce a coating on the wound surface.

What is claimed is: 
     
         1 . A non-thermal equilibrium plasma treated bioresorbable material for use in coating a wound. 
     
     
         2 . A material for use in coating a wound as claimed in  claim 1 , wherein the bioresorbable material is a biopolymer, a biodegradable polymer, a protein or a mixture thereof. 
     
     
         3 . A material for use in coating a wound as claimed in  claim 2 , comprising a protein including collagen, fibrin or fibronecin; a biopolymer including chitin, hyaluronan, chitosan, alginates or cellulose; or a biodegradable polymer including PLGA, polylactic acid, polycaprolactone or polyglactin. 
     
     
         4 . A material for use in coating a wound as claimed in  claim 1 , comprising one of: blood, blood plasma or a blood constituent. 
     
     
         5 . A material for use in coating a wound as claimed in  claim 1 , further comprising one of a pharmaceutical agent or a biologically active compound or combinations thereof. 
     
     
         6 . A material for use in coating a wound as claimed in  claim 5 , comprising one or more of a drug, enzyme, cell, protein or DNA. 
     
     
         7 . A material for use in coating a wound as claimed in  claim 1 , further including one or more of anti-cancer drugs, anti-inflammatory drugs, immuno-suppressants, antibiotics, antimicrobials, heparin, a functional protein, a regulatory protein, structural proteins, oligo-peptides, antigenic peptides, nucleic acids, immunogens, glycosaminoglycans. 
     
     
         8 . A material for use in coating a wound as claimed in  claim 1 , further including one or more of polypeptides, polyglycans, hormones, lipids, interferons, cartilage, therapeutic biologic agents both cellular and synthetically derived, autologous, homologous and allographic and zenographic biologic agents, autologous or homologous, recombinant and synthetic derived blood cells and products containing antimicrobial or antibiotic agents, bacteriostatic agents, stem cells, stromal cells; fibroblast derived Human Dermal Collagen, matrix proteins, growth factors and cytokines, fibronectin, cells found in loose connective tissue such as endothelial cells, cells found in adipose tissue, macrophages, monocytes, adipocytes, pericytes, reticular cells found in bone marrow stroma or cultured autologous keratinocytes.