Lactic acid bacteria capable of preventing and/or treating senescence and dementia

Abstract

The present invention provides a novel lactic acid bacterium having antioxidant and anti-aging functions and a dementia alleviation effect, and more specifically, provides Lactobacillus pentosus var. plantarum C29 KCCM11291P and Lactobacillus curvatus C3 KCCM430009. In addition, the present invention provides an antioxidant and anti-aging pharmaceutical composition and a dietary supplement containing the Lactobacillus pentosus var. plantarum C29 KCCM11291P or Lactobacillus curvatus C3 KCCM430009 of the present invention as an active ingredient, and a composition for preventing or treating dementia and a dietary supplement for preventing or alleviating dementia, containing Lactobacillus pentosus var. plantarum C29 KCCM11291P or Lactobacillus curvatus C3 KCCM430009 as an active ingredient. Additionally, the present invention provides a composition for preventing or treating dementia, containg a fermentation composition, as an active ingredient, fermented by Lactobacullus pentosus var. plantarum C29 KCCM11291P or Lactobacillus curvatus C3 KCCM430009.

1 .  Lactobacillus pentosus var. plantarum  C29 KCCM11291P. 
     
     
         2 . An antioxidant and anti-aging pharmaceutical composition comprising a  Lactobacillus pentosus var. plantarum  C29 KCCM11291P strain as an active ingredient. 
     
     
         3 . A pharmaceutical composition for preventing or treating dementia, the pharmaceutical composition comprising a  Lactobacillus pentosus var. plantarum  C29 KCCM11291P strain as an active ingredient. 
     
     
         4 . A health dietary supplement with antioxidant and anti-aging effects, the health dietary supplement comprising a  Lactobacillus pentosus var. plantarum  C29 KCCM11291P strain as an active ingredient. 
     
     
         5 . A health dietary supplement for preventing or improving dementia, the health dietary supplement comprising a  Lactobacillus pentosus var. plantarum  C29 KCCM11291P strain as an active ingredient. 
     
     
         6 . The pharmaceutical composition of  claim 3 , wherein the dementia is selected from the group consisting of senile dementia, Alzheimer' s disease, vascular dementia, Lewy body dementia, frontotemporal dementia, Parkinson's dementia, Huntington's dementia, dementia induced by normal pressure hydrocephalus, dementia induced by a head injury, and dementia induced by a material. 
     
     
         7 . The health dietary supplement of  claim 5 , wherein the dementia is selected from the group consisting of senile dementia, Alzheimer' s disease, vascular dementia, Lewy body dementia, frontotemporal dementia, Parkinson's dementia, Huntington's dementia, dementia induced by normal pressure hydrocephalus, dementia induced by a head injury, and dementia induced by a material. 
     
     
         8 . An antioxidant and anti-aging pharmaceutical composition comprising a  Lactobacillus curvatus  C3 KCCM43009 strain as an active ingredient. 
     
     
         9 . A pharmaceutical composition for preventing or treating dementia, the pharmaceutical composition comprising a  Lactobacillus curvatus  C3 KCCM43009 strain as an active ingredient. 
     
     
         10 . A health dietary supplement with antioxidant and anti-aging effects, the health dietary supplement comprising a  Lactobacillus curvatus  C3 KCCM43009 strain as an active ingredient. 
     
     
         11 . A health dietary supplement for preventing or improving dementia, the health dietary supplement comprising a  Lactobacillus curvatus  C3 KCCM43009 strain as an active ingredient. 
     
     
         12 . The pharmaceutical composition of  claim 9 , wherein the dementia is selected from the group consisting of senile dementia, Alzheimer's disease, vascular dementia, Lewy body dementia, frontotemporal dementia, Parkinson's dementia, Huntington's dementia, dementia induced by normal pressure hydrocephalus, dementia induced by a head injury, and dementia induced by a material. 
     
     
         13 . The health dietary supplement of  claim 11 , wherein the dementia is selected from the group consisting of senile dementia, Alzheimer's disease, vascular dementia, Lewy body dementia, frontotemporal dementia, Parkinson's dementia, Huntington's dementia, dementia induced by normal pressure hydrocephalus, dementia induced by a head injury, and dementia induced by a material. 
     
     
         14 . A composition for preventing or treating dementia, the composition comprising a fermentation composition fermented by a  Lactobacillus pentosus var. plantarum  C29 KCCM11291P strain or a  Lactobacillus curvatus  C3 KCCM43009 strain as an active ingredient. 
     
     
         15 . The composition of  claim 14 , wherein the fermentation composition is selected from the group consisting of a soybean or defatted soybean fermentation composition, a  kalopanax  fermentation composition, a ginseng fermentation composition, and a  condonopsis lanceolata  fermentation composition. 
     
     
         16 . The composition of  claim 14  or  15 , wherein the dementia is selected from the group consisting of senile dementia, Alzheimer's disease, vascular dementia, Lewy body dementia, frontotemporal dementia, Parkinson's dementia, Huntington's dementia, dementia induced by normal pressure hydrocephalus, dementia induced by a head injury, and dementia induced by a material. 
     
     
         17 . The composition of  claim 15 , wherein the dementia is selected from the group consisting of senile dementia, Alzheimer's disease, vascular dementia, Lewy body dementia, frontotemporal dementia, Parkinson's dementia, Huntington's dementia, dementia induced by normal pressure hydrocephalus, dementia induced by a head injury, and dementia induced by a material.