US2015299661A1PendingUtilityA1

Pluripotent stem cells obtained from dental pulp

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Assignee: UNVERSITAT INTERNAC DE CATALUNYAPriority: Jul 21, 2009Filed: Nov 11, 2014Published: Oct 22, 2015
Est. expiryJul 21, 2029(~3 yrs left)· nominal 20-yr term from priority
Inventors:Maher Al-Atari Abou-AsiNúria Casals FarréLluís Giner TarridaEduardo Ferrés Padró
A61P 25/00A61P 1/16A61P 19/00C12N 5/0664C12N 2500/25A61K 35/28C12N 5/0607C12N 2501/135C12N 2501/235A61K 35/32
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Claims

Abstract

The present invention relates to pluripotent stem cells obtained from the dental pulp of patients of different ages, the invention furthermore comprises cultures of said cells, means for obtaining them and pharmaceutical compositions comprising them, as well as their application in tissue regeneration.

Claims

exact text as granted — not AI-modified
1 . An isolated dental pulp pluripotent stem cell that expresses at least the genes NANOG, SOX2, SSEA4, OCT3/4, CD105, CD13, c-Myc and CD90, and does not express the genes CD34, CD45, CD73 and CD44. 
     
     
         2 . (canceled) 
     
     
         3 . The stem cell according to  claim 1 , characterized in that it is a human cell. 
     
     
         4 . The stem cell according to  claim 1  with accession number DSM ACC3002 given by the institution DSMZ-Deutsche Sammlung von Mikroorganismen and Zellkulturen GmbH. 
     
     
         5 - 8 . (canceled) 
     
     
         9 . A pharmaceutical composition comprising an effective amount of the pluripotent stem cell as defined in  claim 1  and a pharmaceutically acceptable carrier. 
     
     
         10 - 14 . (canceled)

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