Compositions for treatment of xerostomia and for tooth treatment

Abstract

The present application provides an oral care composition comprising: a) emu oil; and one or more of the following: b) one or more emulsifying agents; c) one or more protease enzymes; d) one or more soluble calcium phosphate remineralizing agents; e) one or sore whitening agents.

1 . An oral care composition comprising:
 a) emu oil;   and one or more of the following:   b) one or more emulsifying agents;   c) one or more protease enzymes;   d) one or more soluble calcium phosphate remineralizing agents;   e) one or more whitening agents.   
     
     
         2 . The composition of  claim 1  comprising:
 a) emu oil; 
 and two or more of the following: 
 b) one or more emulsifying agents; 
 c) one or more protease enzymes; 
 d) one or more soluble calcium phosphate remineralizing agents; 
 e) one or more whitening agents; or 
 a) emu oil; 
 and three or more of the following: 
 b) one or more emulsifying agents; 
 c) one or more protease enzymes; 
 d) one or more soluble calcium phosphate remineralizing agents; 
 e) one or more whitening agents; or 
 a) emu oil; 
 b) one or more emulsifying agents; 
 c) one or more protease enzymes; 
 d) one or more soluble calcium phosphate remineralizing agents; 
 e) one or more whitening agents. 
 
     
     
         3 - 4 . (canceled) 
     
     
         5 . The composition of  claim 2 , wherein one or more of the protease enzymes are selected from the group consisting of papain, trypsin, chymotrypsin, aminopeptidase, carboxypeptidase, pepsin, and cathepsin. 
     
     
         6 . The composition of  claim 2 , wherein the one or more whitening agents are selected from the group consisting of carbamide peroxide and hydrogen peroxide. 
     
     
         7 . The composition of  claim 2 , wherein the one or more soluble calcium phosphate remineralizing agents are selected from the group consisting of dibasic calcium phosphate, monocalcium phosphate, tricalcium phosphate, and tetracalcium phosphate. 
     
     
         8 . The composition of  claim 2 , wherein the one or more emulsifying agents are phospholipids. 
     
     
         9 . The composition of  claim 8 , wherein the phospholipids; are soy lecithin. 
     
     
         10 - 17 . (canceled) 
     
     
         18 . The composition of  claim 2 , wherein the composition is formulated as a tablet, a bilayer tablet, a multilayer tablet, chewing gum, a toothpaste, a lozenge, a powder, a gel, a viscous gel, an ointment, a cream, a liquid, a mouthwash, or a candy. 
     
     
         19 . (canceled) 
     
     
         20 . The composition of  claim 18 , wherein the composition is formulated as a bilayer tablet and the bilayer tablet comprises a rapidly disintegrating layer and a slowly eroding layer. 
     
     
         21 - 29 . (canceled) 
     
     
         30 . A method of treating a subject suffering from xerostomia which comprises administering to the subject, in an amount effective to treat the xerostomia, a composition of  claim 1 . 
     
     
         31 . The method of  claim 30 , wherein the composition further whitens teeth in the subject's mouth, remineralizes teeth in the subject's mouth, reduces dental sensitivity of the subject or treats dental caries of the subject. 
     
     
         32 - 37 . (canceled) 
     
     
         38 . The method of  claim 30 , wherein the subject has an autoimmune disease, diabetes, Sjögren's syndrome, or has recently undergone radiation therapy or chemotherapy, or the subject is concurrently taking one or more medications that cause xerostomia. 
     
     
         39 . (canceled) 
     
     
         40 . An oral car composition for whitening teeth comprising one or more whitening agents, wherein the composition is formulated as a bilayer tablet comprising:
 (i) slowly eroding layer,   (ii) a slowly eroding layer,   wherein the one or more whitening agents are each oxidizing agents and are each present only in the rapidly disintegrating layer.   
     
     
         41 - 43 . (canceled) 
     
     
         44 . The composition of  claim 40 , further comprising one or more of the following:
 a) emu oil;   b) one or more emulsifying agents;   c) one or more protease enzymes;   d) one or more soluble calcium phosphate remineralizing agents.   
     
     
         45 - 50 . (canceled) 
     
     
         51 . A method of treating a subject suffering from xerostomia or whitening teeth in a subject's mouth which comprises administering to the subject, in an amount effective to treat the xerostomia or whiten the teeth, a composition of  claim 44 . 
     
     
         52 . (canceled) 
     
     
         53 . An oral care composition comprising:
 a) one or more omega fatty acids;   and one or more of the following:   b) one or more emulsifying agents;   c) one or more protease enzymes;   d) one or more soluble calcium phosphate remineralizing agents;   e) one or more whitening agents.   
     
     
         54 . The composition of  claim 52  comprising:
 a) one or more omega fatty acids; 
 and two or more of the following: 
 b) one or more emulsifying agents; 
 c) one or more protease enzymes; 
 d) one or more soluble calcium phosphate remineralizing agents; 
 e) one or more whitening agents; or 
 a) one or more omega fatty acids; 
 and three or more of the following: 
 b) one or more emulsifying agents; 
 c) one or more protease enzymes; 
 d) one or more soluble calcium phosphate remineralizing agents; 
 e) one or more whitening agents; or 
 a) one or more omega fatty acids; 
 b) one or more emulsifying agents; 
 c) one or more protease enzymes; 
 d) one or more soluble calcium phosphate remineralizing agents; 
 e) one or more whitening agents. 
 
     
     
         55 - 56 . (canceled) 
     
     
         57 . The composition of  claim 54 , wherein the one or more omega fatty acids comprise one or more of omega-3 fatty acids or omega-6 fatty acids. 
     
     
         58 . The composition of  claim 57 , wherein the omega-3 fatty acid is alpha-linoleic acid and the omega-6 fatty acid is gamma-linoleic acid. 
     
     
         59 . A method of treating a subject suffering from xerostomia or whitening teeth in a subject's mouth which comprises administering to the subject, in an amount effective to treat the xerostomia or whiten the teeth, a composition of  claim 54 . 
     
     
         60 . (canceled)