Composition comprising myricetin as active ingredient for enhancing exercise performance or fatigue recovery

Abstract

Provided is a composition containing myricetin or a pharmaceutically available salt thereof as an active ingredient. The composition increases exercise capacity and enhances physical strength. In addition, the composition prevents aging and recovers from fatigue. The composition increases energy efficiency by improving the function of mitochondria, and also has an antiobesity effect by increasing energy consumption. Therefore, the composition may be significantly applied in a functional food or medicine field.

1 . A pharmaceutical composition for enhancing exercise capacity or recovering from fatigue, comprising:
 myricetin or a pharmaceutically available salt thereof as an active ingredient.   
     
     
         2 . (canceled) 
     
     
         3 . (canceled) 
     
     
         4 . (canceled) 
     
     
         5 . (canceled) 
     
     
         6 . The composition of  claim 1 , which increases oxidative metabolism of mitochondria. 
     
     
         7 . The composition of  claim 1 , which increases expression of a peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α), nuclear respiratory factor-1 (NRF-1) or peroxisome proliferator-activated receptor-δ (PPAR-δ) gene. 
     
     
         8 . (canceled) 
     
     
         9 . (canceled) 
     
     
         10 . The composition of  claim 1 , which increases expression of a sirtuin-1 (SIRT-1) gene. 
     
     
         11 . The composition of  claim 1 , wherein the myricetin is extracted from a source material selected from the group consisting of the bark of Chinese bayberry, clover seeds, leaves of  Lysimachia christinae , Korean  rhododendron , succedanea, and walnut.