US2015266958A1PendingUtilityA1
Amino acid sequences that modulate the interaction between cells of the immune system
Est. expiryDec 15, 2026(~0.4 yrs left)· nominal 20-yr term from priority
Inventors:Guy HermansPeter VerheesenEdward DolkHendricus Renerus Jacobus Mattheus HoogenboomMichael John Scott SaundersHans De HaardRenee De Bruin
A61P 37/02C07K 2317/22C07K 2317/76C07K 2317/31C07K 2319/31C07K 16/2818C07K 2317/569C07K 14/76A61P 29/00C07K 16/2827C07K 2317/94C07K 16/2803C07K 2317/35A61K 47/643C07K 2317/567C07K 2317/24C07K 2317/565C07K 2317/92
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Claims
Abstract
The present invention relates to amino acid sequences that block the interaction between (a target on) an antigen presenting cell (APC) and (a target on) a T-cell. More particularly, the present invention relates to amino acid sequences that are directed against (as defined herein) a target on an APC (also referred to herein as “APC target”) or a target on a T-cell (also referred to herein as “T-cell target”). The invention further relates to compounds or constructs, and in particular proteins and polypeptides, that comprise or essentially consist of one or more such amino acid sequences.
Claims
exact text as granted — not AI-modified1 .- 441 . (canceled)
442 . Amino acid sequence that modulates, inhibits, prevents and/or blocks the interaction between a target on an antigen presenting cell (APC) and CD28.Join the waitlist — get patent alerts
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