US2015231133A1PendingUtilityA1

Use of levocetirizine and montelukast in the treatment of influenza, common cold and inflammation

53
Assignee: INFLAMMATORY RESPONSE RES INCPriority: Jun 16, 2010Filed: May 5, 2015Published: Aug 20, 2015
Est. expiryJun 16, 2030(~3.9 yrs left)· nominal 20-yr term from priority
Inventors:Bruce Chandler May
A61P 37/08A61P 43/00A61P 29/00A61P 31/04A61P 31/12A61P 31/16A61P 11/00A61P 11/02A61K 31/47A61K 31/56A61K 31/495A61K 45/06A61K 31/496
53
PatentIndex Score
0
Cited by
0
References
0
Claims

Abstract

The embodiments described herein include methods and formulations for treating influenza, common cold and associated acute inflammation. The methods and formulations include, but are not limited to, methods and formulations for delivering effective concentrations of levocetirizine and montelukast to a patient in need. The methods and formulations can comprise conventional and/or modified-release elements, providing for drug delivery to the patient.

Claims

exact text as granted — not AI-modified
What is claimed is: 
     
         1 . A method of treating chronic inflammation in a patient in need thereof comprising administering to the patient an effective amount of a combination of levocetirizine and montelukast. 
     
     
         2 . The method of  claim 1 , wherein the chronic inflammation is non-IgE-mediated inflammation. 
     
     
         3 . The method of  claim 1 , wherein the chronic inflammation is chronic rhinosinusitis. 
     
     
         4 . The method of  claim 1 , wherein the chronic inflammation is a combination of non-IgE-mediated and IgE-mediated inflammation. 
     
     
         5 . The method of  claim 1 , wherein the patient has nasal polyps. 
     
     
         6 . The method of  claim 1 , wherein the combination is administered in a sequential manner. 
     
     
         7 . The method of  claim 1 , wherein the combination is administered in a substantially simultaneous manner. 
     
     
         8 . The method of  claim 1 , further comprising the administration of a steroid. 
     
     
         9 . The method of  claim 1 , wherein the combination is administered to the patient by one or more of the routes consisting of enteral, intravenous, intraperitoneal, inhalation, intramuscular, subcutaneous and oral. 
     
     
         10 . The method of  claim 9 , wherein the levocetirizine and montelukast are administered by the same route. 
     
     
         11 . A method of treating acute nasal and sinus inflammation in a patient in need thereof comprising administering to the patient an effective amount of a combination of levocetirizine and montelukast. 
     
     
         12 . The method of  claim 11 , wherein the acute inflammation is caused by a viral infection. 
     
     
         13 . The method of  claim 12 , wherein the viral infection is caused by a virus selected from the group consisting of: rhinovirus, coronavirus, influenza, human parainfluenza virus, human respiratory syncytial virus, adenovirus, enterovirus, and metapneumovirus or Epstein Barr virus. 
     
     
         14 . The method of  claim 11 , wherein the combination is administered in a sequential manner. 
     
     
         15 . The method of  claim 11 , wherein the combination is administered in a substantially simultaneous manner. 
     
     
         16 . A method of treating influenza in a patient in need thereof comprising administering to the patient an effective amount of a combination of levocetirizine and montelukast. 
     
     
         17 . The method of  claim 16 , wherein the combination is administered at the onset of symptoms. 
     
     
         18 . The method of  claim 16 , wherein the combination is administered in a sequential manner. 
     
     
         19 . The method of  claim 16 , wherein the combination is administered in a substantially simultaneous manner. 
     
     
         20 . A method of treating cold symptoms in a patient in need thereof comprising administering to the patient an effective amount of a combination of levocetirizine and montelukast. 
     
     
         21 . The method of  claim 20 , wherein the combination is administered at the onset of symptoms. 
     
     
         22 . The method of  claim 20 , wherein the combination is administered in a sequential manner. 
     
     
         23 . The method of  claim 20 , wherein the combination is administered in a substantially simultaneous manner.

Join the waitlist — get patent alerts

Track US2015231133A1 — get alerts on status changes and closely related new filings.

We store only your email — no account needed. See our privacy policy.