Detection of relaxation abnormality in heart tissue

Abstract

A chronically implanted medical device, connected to a medical electrical lead that includes a sensor, is used to detect diastolic dysfunction. A LV accelerometer signal is sensed through the sensor. Based on the LV accelerometer signal, a determination is made as to whether diastolic dysfunction data exists.

1 . An automated method to determine and deliver therapy for diastolic dysfunction through a chronically implanted medical device connected to a medical electrical lead, the method comprising:
 sensing a first signal through a implantable mechanical sensor affixed to the medical electrical lead, the first sensed data comprising complete contraction period data, wherein the complete contraction period is a PQRS complex;   determining a first diastolic dysfunction data exists in response to the sensed first signal;   delivering therapy to tissue in response to determining a first diastolic dysfunction data exists;   sensing a second signal through the implantable mechanical sensor; and   determining a second diastolic dysfunction data exists in response to the sensed second signal, the second diastolic dysfunction data reflects less diastolic dysfunction than the first diastolic dysfunction data.   
     
     
         2 . The method of  claim 1  wherein the therapy is one of stimulation therapy and agent delivery. 
     
     
         3 . The method of  claim 2  further comprising:
 determining termination criteria detected; and 
 ceasing delivery of stimulation therapy in response to determining detection of termination criteria. 
 
     
     
         4 . The method of  claim 1  wherein stimulation therapy is one of electrical stimulation and agent dosage. 
     
     
         5 . The method of  claim 3  further comprising:
 ceasing delivery of stimulation therapy. 
 
     
     
         6 . An automated method to determine and deliver therapy for diastolic dysfunction through a chronically implanted medical device, the method comprising:
 sensing a first signal through a implantable mechanical sensor affixed to a housing for the implanted medical device, the first signal includes complete contraction data;   comparing the complete contraction data to baseline data, wherein the complete contraction period is a PQRS complex;   determining whether diastolic dysfunction data exists; and   delivering therapy to tissue in response to determining the diastolic dysfunction data exists.   
     
     
         7 . The method of  claim 6  wherein the therapy is one of stimulation therapy and agent delivery. 
     
     
         8 . The method of  claim 7  further comprising:
 determining termination criteria detected; and 
 ceasing delivery of stimulation therapy in response to determining termination criteria detected. 
 
     
     
         9 . The method of  claim 8  wherein stimulation therapy is one of electrical stimulation and agent dosage. 
     
     
         10 . A system to determine and deliver therapy for diastolic dysfunction through a chronically implanted medical device connected to a medical electrical lead, the system comprising:
 sensing means for sensing a first signal through a implantable mechanical sensor affixed to the medical electrical lead, the first sensed data comprising complete contraction period data, wherein the complete contraction period is a PQRS complex;   processing means for determining a first diastolic dysfunction data exists in response to the sensed first signal;   delivering means for delivering therapy to tissue in response to determining a first diastolic dysfunction data exists;   sensing means for sensing a second signal through the implantable mechanical sensor; and   processing means for determining a second diastolic dysfunction data exists in response to the sensed second signal, the second diastolic dysfunction data reflects less diastolic dysfunction than the first diastolic dysfunction data.   
     
     
         11 . The system of  claim 10  wherein the therapy is one of stimulation therapy and agent delivery. 
     
     
         12 . The system of  claim 11  further comprising:
 processing means for determining termination criteria detected; and 
 processing means for ceasing delivery of stimulation therapy in response to determining detection of termination criteria. 
 
     
     
         13 . The system of  claim 11  wherein stimulation therapy is one of electrical stimulation and agent dosage. 
     
     
         14 . The system of  claim 13  further comprising:
 processing means for ceasing delivery of stimulation therapy. 
 
     
     
         15 . A system to determine and deliver therapy for diastolic dysfunction through a chronically implanted medical device connected to a medical electrical lead, the system comprising:
 sensing means for sensing a first signal through a implantable mechanical sensor affixed to the medical electrical lead, the first sensed data comprising complete contraction period data, wherein the complete contraction period is a PQRS complex;   processing means for determining a first diastolic dysfunction data exists in response to the sensed first signal;   delivering means for delivering therapy to tissue in response to determining a first diastolic dysfunction data exists;   sensing means for sensing a second signal through the implantable mechanical sensor; and   processing means for determining a second diastolic dysfunction data exists in response to the sensed second signal.   
     
     
         16 . The system of  claim 15  wherein the second diastolic dysfunction data reflects less diastolic dysfunction than the first diastolic dysfunction data. 
     
     
         17 . The system of  claim 15  wherein stimulation therapy is electrical stimulation. 
     
     
         18 . The system of  claim 15  wherein stimulation therapy is agent dosage.