Composition, method and kit for enhancing hair

Abstract

Compositions for application and methods of application of a composition to modify hair. In one embodiment, a composition includes a compound (molecule) represented by: wherein A and B are individually selected from a hydrogen, a hydroxyl group and a halogen, with the proviso that when one of A and B is a hydroxyl group, the other of A and B is a hydrogen and when one of A and B is a halogen, the other of A and B is a halogen or a hydrogen; wherein Z is, for example, an aryl moiety; and wherein X 1 and X 2 are, for example, individually selected from a hydrogen and an alkyl moiety, wherein R 1 and R 2 are individually selected from an oxo, a hydroxyl or an ester group; wherein y is 0 or 1, x is 0 or 1 and x and y are not both 1, or a salt.

What is claimed is: 
     
         1 . A composition comprising a compound of the formula: 
       
         
           
           
               
               
           
         
         wherein the dashed bonds represent a single or double bond; R and R′ are individually selected from the group consisting of hydrogen, a C 1 -C 6  straight or branched chain alkyl; X is selected from the group consisting of a halide, a halide containing group or a hydrogen; y is 0 or 1, x is 0 or 1 and x and y are not both 1 or not both 0; or a salt thereof. 
       
     
     
         2 . A composition of  claim 1 , wherein the compound has the formula: 
       
         
           
           
               
               
           
         
       
     
     
         3 . A composition of  claim 2 , wherein the compound has the formula: 
       
         
           
           
               
               
           
         
       
     
     
         4 . A composition of  claim 2 , wherein the compound has the formula: 
       
         
           
           
               
               
           
         
       
     
     
         5 . A composition of  claim 2 , wherein the compound has the formula: 
       
         
           
           
               
               
           
         
       
     
     
         6 . A composition of  claim 2 , wherein the compound has the formula: 
       
         
           
           
               
               
           
         
       
     
     
         7 . The composition of  claim 1 , further comprising a dermatologically acceptable carrier. 
     
     
         8 . A method comprising:
 directly applying to dermis or hair on the dermis an amount of a composition comprising a compound of the formula:   
       
         
           
           
               
               
           
         
         wherein the dashed bonds represent a single or double bond, R and R′ are individually selected from the group consisting of hydrogen, a C 1 -C 6  straight or branched chain alkyl, X is selected from the group consisting of a halide, a halide containing group or a hydrogen, y is 0 or 1, x is 0 or 1 and x and y are not both 1, or a salt thereof. 
       
     
     
         9 . The method of  claim 7 , wherein the dermis includes an eyelid. 
     
     
         10 . The method of  claim 8 , wherein the compound has the formula: 
       
         
           
           
               
               
           
         
       
     
     
         11 . The method of  claim 8 , wherein the compound has the formula: 
       
         
           
           
               
               
           
         
       
     
     
         12 . The method of  claim 8 , wherein the compound has the formula: 
       
         
           
           
               
               
           
         
       
     
     
         13 . The method of  claim 8 , wherein the compound has the formula: 
       
         
           
           
               
               
           
         
       
     
     
         14 . The method of  claim 8 , wherein the composition further comprises a dermatologically acceptable carrier. 
     
     
         15 . A kit comprising:
 a container;   a composition comprising a compound of the formula:   
       
         
           
           
               
               
           
         
         wherein the dashed bonds represent a single or double bond; R and R′ are individually selected from the group consisting of hydrogen, a C 1 -C 6  straight or branched chain alkyl; X is selected from the group consisting of a halide, a halide containing group or a hydrogen; y is 0 or 1, x is 0 or 1 and x and y are not both 1 or not both 0; or a pharmaceutically acceptable salt thereof, and 
         wherein the container includes an amount of the composition for repeated application over a period. 
       
     
     
         16 . The kit of  claim 15  further comprising an applicator. 
     
     
         17 . The kit of  claim 15 , wherein the compound is selected from at least one of the following: