Combination therapies for b-cell lymphomas comprising administration of anti-cd20 antibody

Abstract

New combined therapeutic regimens for treatment of B-cell lymphomas are disclosed which comprise, in particular, administration of anti-CD20 antibodies to patients having low-, intermediate- or high-grade non-Hodgkin's lymphomas.

What is claimed is: 
     
         1 . A method of treating an adult patient with relapsed low grade or follicular CD20-positive lymphoma comprising administering rituximab to the patient, monitoring for adverse events during therapy and discontinuing therapy if a grade 3 or grade 4 adverse event occurs in the patient, and wherein the adverse event is grade 3 or grade 4 arrhythmia. 
     
     
         2 . The method of  claim 1  wherein the adult patient has not responded to primary therapy.