Process for the Preparation of N-Monosubstituted beta-Amino Alcohols

Abstract

A process is disclosed for the preparation of a compound of formula and/or an addition salt of a proton acid, wherein R 1 and R 2 independently represent alkyl, cycloalkyl, aryl or aralkyl, each aryl or aralkyl being optionally further substituted with alkyl, alkoxy and/or halogen.

1 - 8 . (canceled) 
     
     
         9 . A compound of formula 
       
         
           
           
               
               
           
         
         and its addition salts of proton acids, wherein R 1  represents 
         furanyl, benzofuranyl, isobenzofuranyl, thienyl or benzo[b]thienyl, each being optionally substituted with halogen, linear or branched C 1-4  alkyl, linear or branched C 1-4  alkoxy, C 3 - 6  cycloalkyl, CF 3 , C 2 F 5 , OCF 3  or OC 2 F 5 ; and wherein R 2  is selected from the group consisting of linear or branched C 1-8  alkyl, C 3-8  cycloalkyl, phenyl, naphthyl, furanyl, benzofuranyl, thienyl, benzo[b]thienyl and aralkyl, wherein the alkyl moiety of the aralkyl residue is linear C 1-4  alkyl, and the aryl moiety is selected from the group consisting of phenyl, naphthyl, furanyl, benzofuranyl, thienyl and benzo[b]thienyl, each aryl or aralkyl being optionally substituted with halogen, linear or branched C 1-4  alkyl, linear or branched C 1-4  alkoxy, C 3-6  cycloalkyl, CF 3 , C 2 F 5  OCF 3  or OC 2 F 5  with the exception of the compound wherein R 1  represents thienyl and R 2  represents benzyl. 
       
     
     
         10 - 11 . (canceled) 
     
     
         12 . A compound of formula 
       
         
           
           
               
               
           
         
         and its addition salts of proton acids. 
       
     
     
         13 - 20 . (canceled)