Analyte Monitoring Device and Methods of Use

Abstract

In aspects of the present disclosure, a multi compatible or universal blood glucose monitoring unit including a calibration unit is integrated with one or more components of an analyte monitoring system to provide compatibility with in vitro test strip that require calibration code and test strips that do not require calibration code. Also disclosed are methods, systems, devices and kits for providing the same.

What is claimed is: 
     
         1 . A device, comprising:
 a test strip receiving port configured to receive coded in vitro glucose test strips that require user calibration action to calibrate the coded in vitro glucose test strips and non-coded in vitro glucose test strips that do not require user calibration action to calibrate the non-coded in vitro glucose test strips; and   a processor configured to determine glucose concentration from the coded or the non-coded in vitro glucose test strips received in the test strip receiving port by determining if a received in vitro glucose test strip is a coded or a non-coded test strip, selecting a coded or a non-coded processing algorithm to process a signal from the coded or the non-coded in vitro test strip, and processing the signal from the coded or the non-coded in vitro test strip to determine a glucose value.   
     
     
         2 . The device of  claim 1 , further comprising programming to automatically determine if the received in vitro glucose test strip is the coded or the non-coded test strip. 
     
     
         3 . The device of  claim 1 , further comprising user-selectable inputs to identify the received in vitro glucose test strip as the coded or the non-coded test strip. 
     
     
         4 . The device of  claim 1 , wherein the processor is programmed to generate a request for a calibration code if the coded test strip is received in the test strip receiving port. 
     
     
         5 . The device of  claim 1 , further comprising an insulin administration system integrated with the device. 
     
     
         6 . The device of  claim 1 , wherein the processor is programmed to use the determined glucose value to calibrate signals from an in vivo glucose sensor to generate calibrated in vivo glucose values. 
     
     
         7 . The device of  claim 6 , wherein the processor is programmed to use a single glucose value to calibrate the signals from the in vivo glucose sensor. 
     
     
         8 . The device of  claim 6 , wherein the processor is programmed to calibrate the signals from the in vivo glucose sensor when the determined glucose value is within an acceptable range. 
     
     
         9 . The device of  claim 6 , wherein the processor is programmed to determine a rate of change of a glucose level and calibrate the in vivo glucose sensor when the determined rate of change is within an acceptable range. 
     
     
         10 . The device of  claim 6 , wherein the in vivo glucose sensor includes a plurality of electrodes, wherein the plurality of electrodes include a working electrode comprising an analyte-responsive enzyme and a mediator, wherein at least one of the analyte-responsive enzyme and the mediator is chemically bonded to a polymer disposed on the working electrode, and wherein the at least one of the analyte-responsive enzyme and the mediator is crosslinked with the polymer. 
     
     
         11 . A method, comprising:
 receiving, at a test strip receiving port, one of a coded in vitro glucose test strip that requires user calibration action to calibrate the test strip or a non-coded in vitro glucose test strip that does not require user calibration action to calibrate the test strip; and   determining, using one or more processors, glucose concentration from the coded or the non-coded in vitro glucose test strips received in the test strip receiving port by determining, using the one or more processors, if a received in vitro glucose test strip is the coded or the non-coded test strip, selecting, using the one or more processors, a coded or a non-coded processing algorithm to process a signal from the in vitro test strip, and processing, using the one or more processors, the signal from the in vitro test strip to determine a glucose value.   
     
     
         12 . The method of  claim 11 , further comprising automatically determining if the received in vitro glucose test strip is the coded or the non-coded test strip. 
     
     
         13 . The method of  claim 11 , further comprising identifying the received in vitro glucose test strip as the coded or the non-coded test strip with one or more user-selectable inputs. 
     
     
         14 . The method of  claim 11 , further including generating a request for a calibration code if the coded test strip is received in the test strip receiving port. 
     
     
         15 . The method of  claim 11 , further comprising integrally providing an insulin administration system with a user interface. 
     
     
         16 . The method of  claim 11 , further comprising calibrating signals from an in vivo glucose sensor with the determined glucose value to generate calibrated in vivo glucose values. 
     
     
         17 . The method of  claim 16 , further comprising calibrating the signals from the in vivo glucose sensor with a single glucose value. 
     
     
         18 . The method of  claim 16 , further comprising calibrating the signals from the in vivo glucose sensor when the determined glucose value is within an acceptable range. 
     
     
         19 . The method of  claim 16 , determining a rate of change of a glucose level and calibrating the signals from the in vivo glucose sensor when the determined rate of change is within an acceptable range. 
     
     
         20 . The method of  claim 16 , wherein the in vivo glucose sensor includes a plurality of electrodes, wherein the plurality of electrodes include a working electrode comprising an analyte-responsive enzyme and a mediator, wherein at least one of the analyte-responsive enzyme and the mediator is chemically bonded to a polymer disposed on the working electrode, and wherein the at least one of the analyte-responsive enzyme and the mediator is crosslinked with the polymer.