US2015080427A1PendingUtilityA1

Benzoquinoline inhibitors of vesicular monoamine transporter 2

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Assignee: AUSPEX PHARMACEUTICALS INCPriority: Sep 18, 2008Filed: Oct 15, 2014Published: Mar 19, 2015
Est. expirySep 18, 2028(~2.1 yrs left)· nominal 20-yr term from priority
Inventors:Thomas G. GantManouchehr Shahbaz
A61P 43/00A61P 25/16A61P 25/00A61P 25/18A61P 25/14A61P 1/16A61P 21/00A61K 31/4745C07D 455/06C07B 59/00C07B 59/002A61K 45/06C07B 2200/05
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Claims

Abstract

The present invention relates to new benzoquinoline inhibitors of vesicular monoamine transporter 2 (VMAT2), pharmaceutical compositions thereof, and methods of use thereof.

Claims

exact text as granted — not AI-modified
What is claimed is: 
     
         1 . A compound having the structural formula: 
       
         
           
           
               
               
           
         
       
       or a salt thereof, wherein each position represented as D has deuterium enrichment of no less than about 50%. 
     
     
         2 . A pharmaceutical composition comprising a compound as recited in  claim 1  together with a pharmaceutically acceptable carrier.

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