Holder for monolithic sorbents

Abstract

The present invention relates to a holder for monolithic sorbents in which a radial pressure can be exerted over the entire length of the sorbent by a conically tapering clamping tube.

1 . Holder for the accommodation of a monolithic chromatography column at least comprising
 a clamping tube whose inside diameter is constant and whose outside diameter increases uniformly towards the centre, to one end or to both ends and which has one or more slots in the longitudinal direction of the tube   a pressure sleeve consisting of a tube whose inside diameter increases uniformly from one end to the other end and which has at least one flange or groove on the outside   a clamping device   
     
     
         2 . Holder according to  claim 1 , characterised in that the clamping device consists of two screw parts whose inside diameter is greater than the outside diameter of the tube of the pressure sleeve, where one screw part has an external thread and one screw part has an internal thread, which can be screwed together. 
     
     
         3 . Holder according to  claim 1 , characterised in that the holder is made from stainless steel. 
     
     
         4 . Holder according to  claim 1 , characterised in that the outside diameter of the clamping tube increases towards the centre. 
     
     
         5 . Holder according to  claim 1 , characterised in that the holder has two pressure sleeves. 
     
     
         6 . Holder according to  claim 1 , characterised in that the clamping tube has 6 to 12 slots. 
     
     
         7 . Holder according to  claim 1 , characterised in that the slope of the surface shell of the clamping tube is between 1:60 and 1:40. 
     
     
         8 . Holder according to  claim 1 , characterised in that the clamping device is actuated mechanically, hydraulically, pneumatically or electromechanically. 
     
     
         9 . Separating device at least consisting of a holder according  claim 1  and a monolithic chromatography column. 
     
     
         10 . Separating device according to  claim 9 , characterised in that the monolithic chromatography column has a PEEK or PPS cladding. 
     
     
         11 . Separating device according to  claim 9 , characterised in that the monolithic sorbent of the chromatography column has a diameter between 1 mm and 25 mm. 
     
     
         12 . A process for the chromatographic separation of at least two substances comprising subjecting said substances to a separating device according to  claim 9 .