US2015031871A1PendingUtilityA1
RNA-Mediated Gene Modulation
Est. expirySep 16, 2022(expired)· nominal 20-yr term from priority
C12N 15/63C12N 2310/30C12N 2310/14C12N 15/113
56
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Claims
Abstract
An isolated RNA comprising an intron RNA that is released in a cell, thereby modulating the function of a target gene. Also disclosed are a composition comprising a chemokine and an isolated RNA of the invention or a DNA template for the isolated RNA, a composition comprising one or more agents that induce RNA-mediated modulation of the functions of two or more target genes in a cell, and methods of using these compositions for modulating the functions of genes in a cell.
Claims
exact text as granted — not AI-modified1 . An isolated RNA comprising an intron RNA that is released in a cell, thereby modulating the function of a target gene, wherein the isolated RNA does not contain a combination of a splice donor site that includes 5′-GU(A/G)AGU-3′ and a splice acceptor site that includes 5′-CU(A/G)A(C/U)NG-3′.
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