High Fluoride Ion Oral Care Composition and Method for Maintaining Anticaries Activity

Abstract

An oral care composition and method of maintaining anticaries activity of fluoride ion in an oral care composition are described. An oral care composition comprises a fluoride ion source sufficient to maintain a high fluoride content in the composition, an effective amount of a desensitizing agent and water. A method of maintaining anti caries activity of fluoride km in an oral care composition comprises providing an oral care composition comprising fluoride ions, an effective amount of a desensitizing agent and water.

We claim: 
     
         1 . An oral care composition, comprising
 a sufficient amount of a fluoride on source to provide at least about 2,500 ppm of fluoride ions   an effective amount of a desensitizing agent; and   at least about 40 percent by weight water.   
     
     
         2 . The oral care composition of  claim 1 , further comprising a hydrocolloid. 
     
     
         3 . The oral care composition of  claim 2 , wherein the hydrocolloid is selected from the group consisting of xanthan gum, carrageenan gum and combinations thereof. 
     
     
         4 . The oral care composition of  claim 3  wherein the hydrocolloid is carrageenan gum comprising sulfate. 
     
     
         5 . The oral care composition of  claim 2 , wherein the composition comprises about 0.5 percent by weight to about 15 percent by weight of the hydrocolloid based on the total weight of the composition. 
     
     
         6 . The oral care composition of  claim 5 , wherein the composition comprises about 0.5 percent to about 1.5 percent by weight of the hydrocolloid based on the total weight of the composition. 
     
     
         7 . The oral care composition of  claim 1 , wherein the fluoride ion source is present in an amount of about 1% to about 5% by weight. 
     
     
         8 . The oral care composition of  claim 1 , wherein the fluoride ion source is sodium fluoride. 
     
     
         9 . The oral care composition of  claim 1 , wherein the fluoride ion source is selected from the group consisting of potassium fluoride, calcium fluoride, zinc fluoride, zinc ammonium fluoride, lithium fluoride, ammonium fluoride, stannous fluoride, stannous fluorozirconate, sodium monofluorophosphate, potassium monofluorophosphate, laurylamine hydro fluoride, diethylaminoethyloctoylamide hydro fluoride, didecyldimethylammonium fluoride, cetylpyridinium fluoride, dilaurylmorpholinium fluoride, sarcosine stannous fluoride, glycine potassium fluoride, glycine hydrofluoride and combinations thereof. 
     
     
         10 . The oral care composition of  claim 1 , wherein the desensitizing agent is a potassium salt. 
     
     
         11 . The oral care composition of  claim 10 , wherein the potassium salt is potassium nitrate. 
     
     
         12 . The oral care composition of  claim 11 , wherein the composition comprises about 5 percent to about 10 percent by weight of potassium nitrate. 
     
     
         13 . The oral care composition of  claim 10 , wherein the potassium salt is selected from the group consisting of potassium bicarbonate, potassium chloride, potassium citrate, and potassium oxalate. 
     
     
         14 . The oral care composition of claim I, Wherein the desensitizing agent is selected from the group consisting of capsaicin; eugenol; a strontium salt; a zinc salt; a chloride salt and combinations thereof. 
     
     
         15 . The oral care composition of  claim 1 , wherein the composition comprises about 60 percent to about 75 percent by weight water. 
     
     
         16 . The oral care composition of  claim 1 , further comprising at least one further active agent selected from the group consisting of stannous ion agent; triclosan; triclosan monophosphate; chlorhexidine; alexidine; hexetidine; sanguinarine; benzalkonium chloride; salicylanilide; arginate esters; ethyllauryl arginate, bisphenols, domiphen bromide; tetradecylpyridinium chloride; N-tetradecyl-4-ethylpyridinium chloride; octenidine; dell octapinol; nisin; zinc ion agent; copper ion agent; essential oils; furanones; bacteriocins; salts thereof; and combinations thereof. 
     
     
         17 . The oral care composition of  claim 1 , further comprising at least one additive selected from the group consisting of an abrasive silica, an amorphous silica, a humectant, at least one second thickening agent different from the thickening agent of the oral care composition, a stabilizing agent, an antibacterial agent, a sweetener, and a surfactant. 
     
     
         18 . The oral care composition of  claim 1 , wherein the oral care composition is a toothpaste. 
     
     
         19 . An oral care composition, comprising;
 at least about 2,500 ppm of fluoride ions;   about 5 percent to about 10 percent by weight of a potassium salt;   about 40 percent to about 75 percent by weight water; and   about 0.5 percent to about 15 percent by weight of a hydrocolloid selected from the group consisting of xanthan gum, carrageenan gum and combinations thereof.   
     
     
         20 . The oral care composition of  claim 19 , wherein the composition comprises about 0.5 percent to about 1.5 percent by weight of carrageenan gum comprising sulfate. 
     
     
         21 . The oral care composition of  claim 20 , wherein the oral care composition is a toothpaste. 
     
     
         22 . A method of maintaining anti caries activity in an oral care composition, comprising:
 providing an oral care composition comprising at least about 2500 ppm of fluoride ions, an effective amount of a desensitizing agent and at least about 40 percent by weight water; and   providing to the oral care composition about 0.5 percent weight to about 15 percent by weight of a hydrocolloid.   
     
     
         23 . The method of  claim 22 , wherein the hydrocolloid is xanthan gum, 
     
     
         24 . The method of  claim 22 , wherein the hydrocolloid is carrageenan gum comprising sulfate. 
     
     
         25 . The method of  claim 22 , wherein the carrageenan gum comprising sulfate is capable of providing about 100 percent fluoride recovery after four weeks. 
     
     
         26 . The method of  claim 22 , wherein the oral care composition comprises about 60 percent to about 75 percent by weight water. 
     
     
         27 . The method of  claim 22 , wherein the desensitizing agent is potassium nitrate.