US2015011768A1PendingUtilityA1

4-hydroxybenzomorphans

Assignee: RENSSELAER POLYTECH INSTPriority: Nov 5, 2004Filed: Jul 2, 2014Published: Jan 8, 2015
Est. expiryNov 5, 2024(expired)· nominal 20-yr term from priority
A61P 37/06A61P 43/00A61P 25/36A61P 25/30A61P 25/04A61P 25/02A61P 29/00A61P 25/08A61P 3/04A61P 1/12A61P 1/00A61P 11/14A61P 21/02A61P 11/00A61P 1/04A61P 17/04C07D 221/26C07D 489/02C07D 489/00C07D 215/20C07D 215/14C07D 221/28C07D 489/08A61K 31/485
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Claims

Abstract

4-Hydroxybenzomorphans containing carboxamide or thiocarboxamide at the 3-position are useful as analgesics, anti-diarrheal agents, anticonvulsants, antitussives and anti-addiction medications.

Claims

exact text as granted — not AI-modified
I claim: 
     
         1 - 9 . (canceled) 
     
     
         10 . A pharmaceutically acceptable acid addition salt of a compound of formula: 
       
         
           
           
               
               
           
         
         wherein said salt is selected from acetic, benzenesulfonic (besylate), benzoic, camphorsulfonic, citric, ethenesulfonic, fumaric, gluconic, glutamic, hydrobromic, hydrochloric, isethionic, lactic, maleic, malic, mandelic, methanesulfonic, mucic, nitric, pamoic, pantothenic, phosphoric, succinic, sulfuric, tartaric acid or p-toluenesulfonic acid salt.

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