US2015004696A1PendingUtilityA1

Inhibiting cyclin d polypeptides

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Assignee: MAYO FOUNDATIONPriority: Oct 10, 2006Filed: Jul 25, 2014Published: Jan 1, 2015
Est. expiryOct 10, 2026(~0.2 yrs left)· nominal 20-yr term from priority
Inventors:Rodger E. TiedemannAlexander Keith StewartAaron David SchimmerXinliang Mao
G01N 33/566A61K 31/56G01N 33/6872A61K 31/573C07K 14/4738A61K 38/00A61K 31/7076
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Claims

Abstract

This document involves methods and materials related to inhibiting cyclin D polypeptide activity. For example, this document provides methods and materials that can be used to (1) identify mammals or cells in need of cyclin D polypeptide inhibition and (2) administer an agent capable of inhibiting cyclin D polypeptide activity.

Claims

exact text as granted — not AI-modified
What is claimed is: 
     
         1 . A method for reducing cyclin D polypeptide activity within a cell, wherein said method comprises:
 (a) identifying a cell in need of reduced cyclin D polypeptide activity, and   (b) administering an agent to said cell, wherein said agent is β-lapachone, dihydrogambogic acid, pristimerin, or kinetin riboside.

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