US2014377305A1PendingUtilityA1
Method for treating disease associated with transcription activation by nf-kb
Est. expiryApr 2, 2032(~5.7 yrs left)· nominal 20-yr term from priority
Inventors:Masayoshi Yamaguchi
A61P 9/00A61P 43/00A61P 37/08A61P 31/14A61P 35/00A61P 31/04A61P 31/20A61P 29/00A61P 31/12A61P 31/00A61P 27/02A61P 1/18A61P 1/00A61P 17/06A61P 13/12A61P 25/00A61P 1/04A61P 11/08A61P 17/00A61P 11/00A61P 19/02A61P 11/06A61P 19/06A61P 1/16A61P 11/02A61K 36/03
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Claims
Abstract
A method for treating a disease associated with transcription activation by NF-κB by administering a composition for inhibiting transcription activation by NF-κB to a patient in need of treatment of the disease. The composition contains a fraction having a molecular weight of 3,000 or less obtained by purifying a water extract of Sargassum horneri as an active ingredient.
Claims
exact text as granted — not AI-modified1 .- 8 . (canceled)
9 . A method for treating a disease associated with transcription activation by NF-κB, the method comprising administering a composition for inhibiting transcription activation by NF-κB to a patient in need of treatment of the disease, wherein the composition contains a fraction having a molecular weight of 3,000 or less obtained by purifying a water extract of Sargassum horneri as an active ingredient.
10 . The method according to claim 9 , wherein the disease associated with transcription activation by NF-κB is a function deterioration of an osteoblast caused by TNF-α increase.
11 . The method according to claim 9 , wherein the disease associated with transcription activation by NF-κB is an articular bone destruction by promotion of osteoclastogenesis from osteoclast precursor cells by RANKL.Join the waitlist — get patent alerts
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