Porphyromonas gingivalis polypeptides and nucleotides

Abstract

The present invention relates to isolated Porphyromanas gingivalis polypeptides and nucleotides. The polypeptides include an amino acid sequence selected from the group consisting of: SEQ. ID. NO. 110; SEQ. ID. NO. 111; SEQ. ID. NO. 112; SEQ. ID. NO. 113; SEQ ID NO: 120; SEQ. ID. NO. 123; SEQ. ID. NO. 124; SEQ. ID. NO. 125; SEQ. ID. NO. 130; SEQ. ID. NO. 131; SEQ. ID. NO. 132; SEQ. ID. NO. 133; SEQ. ID. NO. 135; SEQ. ID. NO. 136; SEQ. ID. NO. 137; SEQ. ID. NO. 138; SEQ. ID. NO. 143; SEQ. ID. NO. 144; SEQ. ID. NO. 145; SEQ. ID. NO. 146; SEQ. ID. NO. 147; SEQ. ID. NO. 148; and amino acid sequences at least 95% identical thereto.

1 .- 4 . (canceled) 
     
     
         5 . An isolated antigenic  Porphyromonas gingivalis  polypeptide comprising the amino acid sequence of SEQ ID NO:145 or a sequence at least 95% identical thereto. 
     
     
         6 . An immunogenic composition directed against  P. gingivalis , comprising an amount of the polypeptide of  claim 5  effective to induce an immune response against  P. gingivalis  and a pharmaceutically acceptable carrier. 
     
     
         7 . The composition as claimed in  claim 6  wherein the pharmaceutically acceptable carrier comprises an adjuvant.