US2014221451A1PendingUtilityA1

Implants for the treatment of dopamine associated states

Assignee: UNIV PENNSYLVANIAPriority: Apr 6, 2006Filed: Feb 7, 2014Published: Aug 7, 2014
Est. expiryApr 6, 2026(expired)· nominal 20-yr term from priority
A61P 43/00A61P 5/00A61P 5/06A61P 25/00A61P 25/16A61P 25/28A61P 25/14A61P 21/00A61P 15/00A61P 15/10A61L 27/34A61L 27/18A61L 31/06A61L 27/54A61L 31/16A61K 31/4045A61L 31/10A61K 9/204A61K 9/0024A61L 31/148A61L 2300/40A61K 31/403A61K 31/517
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Claims

Abstract

Biodegradable implants comprising dopamine modulating compounds are described.

Claims

exact text as granted — not AI-modified
1 . A method of treating a subject for a dopamine associated state, comprising administering to said subject a biodegradable implant, wherein said implant comprises an effective amount of a dopamine modulating compound, such that said subject is treated for said dopamine associated state. 
     
     
         2 - 25 . (canceled) 
     
     
         26 . A biodegradable implant, comprising a dopamine modulating compound and a biodegradable polymer. 
     
     
         27 - 42 . (canceled) 
     
     
         43 . A method for maintaining a plasma level of between about 1 and 40 of a dopamine modulating compound in a subject, comprising administering to said subject an implant comprising a biodegradable polymer and said dopamine modulating compound, such that the plasma level of said compound is maintained for at least one day. 
     
     
         44 - 56 . (canceled) 
     
     
         57 . The method of  claim 1 , wherein the dopamine associated state is Parkinson's disease, and wherein the dopamine modulating compound is ropinirole. 
     
     
         58 - 59 . (canceled)

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