Multi-pole synchronous pulmonary artery radiofrequency ablation catheter

Abstract

A multi-pole synchronous pulmonary artery radiofrequency ablation catheter, wherein an adjustment apparatus is arranged on a control handle; a catheter body is hollow, and a cavity is arranged therein; a lead wire, a temperature sensing wire and a pull wire are arranged in the cavity; one end of the catheter body is flexible, and the flexible end is connected to an annular ring; the annular ring is provided with an electrode group with each electrode connected to the lead wire and temperature sensing wire; the lead wire and temperature sensing wire go through the catheter body and are electrically connected to the control handle. The device uses cold saline perfusion method to protect the vascular intima and possesses advantages of simple operation, short operation time and controllable precise ablation. The device can be used to treat pulmonary hypertension with pulmonary denervation.

1 . A multi-pole synchronous pulmonary artery radiofrequency ablation catheter, comprising:
 a control handle including an adjustment apparatus;   a catheter body being hollow and comprising a cavity arranged in the catheter body; and   an annular ring;   wherein a lead wire, a temperature sensing wire and a pull wire are arranged in the cavity;   wherein one end of the catheter body is flexible, and the flexible end is connected to the annular ring, and wherein the other end of the catheter body is connected to the control handle;   wherein one end of the pull wire is connected to the flexible end, and the other end of the pull wire is connected to the adjustment apparatus on the control handle, the adjustment apparatus adjusts the tension of the pull wire to change a curvature of the flexible end;   a shape memory wire arranged in the annular ring, and one end of the shape memory wire extends to the end of the annular ring and the other end of the shape memory wire passes through the root of the annular ring and is fixed on the flexible end of the catheter body;   wherein the annular ring is provided with an electrode group comprising a plurality of electrodes, and each electrode of the electrode group is connected to the lead wire and temperature sensing wire;   wherein the lead wire and the temperature sensing wire go through the catheter body and are electrically connected to the control handle.   
     
     
         2 . The multi-pole synchronous pulmonary artery radiofrequency ablation catheter according to  claim 1 , wherein an infusion tube is arranged in the cavity of the catheter body and a through hole is arranged on the electrode, the infusion tube extending through the annular ring and connected to the electrode such that transfused fluid flows out from the through hole. 
     
     
         3 . The multi-pole synchronous pulmonary artery radiofrequency ablation catheter according to  claim 1 , wherein the electrode on the annular ring is made of a material selected from the group consisted of platinum-iridium alloy, gold, stainless steel and nickel alloy, with a number in the range of 3-30 electrodes, an electrode diameter in the range of 1.3-2.0 mm, a length in the range of 1.2-4 mm and an edge space between adjacent electrodes in the range of 0.5-10 mm. 
     
     
         4 . The multi-pole synchronous pulmonary artery radiofrequency ablation catheter according to  claim 1 , wherein, the flexible end of the catheter body is provided with a counterbore, an inner diameter of the counterbore fits around an outer diameter of root of the annular ring, the root of the annular ring is inserted and fixed in the counterbore. 
     
     
         5 . The multi-pole synchronous pulmonary artery radiofrequency ablation catheter according to  claim 1 , wherein the flexible end includes a groove, a connector is disposed in the groove, wherein one end of the connector is connected to the pull wire and the other end of the connector is connected to the shape memory wire. 
     
     
         6 . The multi-pole synchronous pulmonary artery radiofrequency ablation catheter according to  claim 1 , wherein the material of the shape memory wire is a shape memory alloy selected from the group consisted of nickel titanium alloy, stainless steel and titanium, with a diameter in the range of 0.25-0.5 mm, the diameter of the annular ring being in the range of 12-40 mm. 
     
     
         7 . The multi-pole synchronous pulmonary artery radiofrequency ablation catheter according to  claim 1 , wherein the flexible end of the catheter body is made of medical polymer materials with a length in the range of 30-80 mm. 
     
     
         8 . The multi-pole synchronous pulmonary artery radiofrequency ablation catheter according to  claim 1 , wherein the connector is connected with a UV-curing adhesive. 
     
     
         9 . The multi-pole synchronous pulmonary artery radiofrequency ablation catheter according to  claim 1 , wherein the joint between the flexible end of the catheter body and the annular ring is sealed. 
     
     
         10 . The multi-pole synchronous pulmonary artery radiofrequency ablation catheter according to  claim 1 , wherein the pull wire is made of stainless steel or nickel-titanium alloy, the pull wire including a coil spring, the coil spring includes a spring sleeve made of a polyimide material. 
     
     
         11 . The multi-pole synchronous pulmonary artery radiofrequency ablation catheter according to  claim 1 , wherein the shape memory wire is configured to bias the annular ring into a circumferential configuration with exposed surfaces of the electrodes facing radially outwardly. 
     
     
         12 . A multi-pole pulmonary artery radiofrequency ablation catheter, comprising:
 a catheter body including a handle;   a lumen member having a proximal end connected to the catheter body and a distal end;   an electrode assembly having a proximal end connected to the distal end of the lumen member, the electrode assembly comprising a longitudinally extending flexible lumen member and a plurality of ablation electrodes disposed along the flexible lumen member, each electrode having a surface exposed at an outer surface of the flexible lumen member, the flexible lumen member being biased into a circumferentially extending configuration wherein exposed surfaces of the electrodes face a radially outward direction when the flexible lumen member is in the circumferentially extending configuration.   
     
     
         13 . The catheter according to  claim 12 , additionally comprising an electrical connection having a proximal portion in the handle and extending from the handle to each of the plurality electrodes and configured to allow energy applied to the proximal portion of the electrical connection to be independently applied to each of the electrodes. 
     
     
         14 . The catheter according to  claim 13 , wherein the electrodes are separated and electrically isolated from each other. 
     
     
         15 . The catheter according to  claim 14 , wherein the electrical connection comprises a plurality of electrical wires connected to the electrode, respectively. 
     
     
         16 . The catheter according to  claim 12 , wherein each electrode further comprises a plurality of through holes and wherein the flexible lumen member includes at least one lumen extending from the proximal end of the flexible lumen member to the through holes on each of the electrodes thereby forming a fluidic connection from the proximal portion of the flexible lumen member to the through holes. 
     
     
         17 - 48 . (canceled)