US2014178500A1PendingUtilityA1

Methods of treating outer eye disorders using high orp acid water and compositions thereof

Assignee: APR NANOTECHNOLOGIES S APriority: Jun 17, 2009Filed: Feb 27, 2014Published: Jun 26, 2014
Est. expiryJun 17, 2029(~2.9 yrs left)· nominal 20-yr term from priority
A61P 27/02A61P 27/12A61K 33/20
43
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Claims

Abstract

The present invention relates to a method of treating an outer eye disorder selected from a cataract, neovascularization, keratitis, epithelium deficiency, or chronic opacity, by administering to the eye a composition comprising acidic electrolytic water. The present invention also relates to a stable acidic electrolyzed oxidizing water characterized by low conductivity, the presence of dissolved chlorine gas (Cl 2 ), hypochlorous acid (HOCl) and chloride ions (Cl − ), and by the presence of negligible quantities of hypochlorite ion (OCl − ).

Claims

exact text as granted — not AI-modified
1 ) A method of treating a condition selected from cataract, ocular keratitis, corneal neovascularization, epithelium deficiency, and chronic opacity in a lens in an animal patient in need thereof, comprising topically administering to an eye of said patient a composition comprising a therapeutically effective amount of a high ORP acidic water. 
     
     
         2 ) The method of  claim 1 , wherein said high ORP acidic water has an ORP of greater than 1100 mV, and a pH of from 0.5 to 5.0. 
     
     
         3 ) The method of  claim 1 , wherein said high ORP acidic water has a NMR half line width using  17 O of from 42 to 60 Hz, and a pH of about 0.5 to about 5.0. 
     
     
         4 ) The method of  claim 1 , wherein said administering step comprises dropping said composition directly into said eye. 
     
     
         5 ) The method of  claim 1 , wherein said administering step comprises applying said composition to said eye with a piece of gauze. 
     
     
         6 ) The method of  claim 1 , wherein said administering step comprises applying said composition to said eye 1 to 20 times per day, for at least 14 days. 
     
     
         7 ) An electrolytic acid water comprising free chlorine, wherein:
 a) from 95% to 99.9% of said free chlorine is present in the form of hypochlorous acid;   b) said water has a pH of from 1.0 to 4.0; and   c) said water has an ORP of greater than 1100 mV.   
     
     
         8 ) An electrolytic acid water comprising free chlorine, wherein:
 a) from 90% to 99.9% of said free chlorine is present in the form of hypochlorous acid;   b) said water has a pH of from 1.0 to 4.0; and   c) said water has an ORP of greater than 1100 mV.   
     
     
         9 ) The electrolytic acid water of  claim 7 , wherein the relative amount of HOCl and Cl 2  is from 99.9% HOCl and 0.1% Cl 2  to 95% HOCl to 5% Cl 2 . 
     
     
         10 ) The electrolytic acid water of  claim 7 , wherein the relative amount of HOCl and Cl 2  is from 99.5% HOCl and 0.5% Cl 2  to 98.5% HOCl to 1.5% Cl 2 . 
     
     
         11 ) The electrolytic acid water of  claim 7 , having a NMR half line width using  17 O of from 42 to 60 Hz. 
     
     
         12 ) The electrolytic acid water of  claim 7 , wherein said water has a conductivity of from 1200 to 1400 uS/cm. 
     
     
         13 ) The electrolytic acid water of  claim 7 , wherein said water maintains 90% of said free chlorine after a storage period of 3 months at room temperature. 
     
     
         14 ) The electrolytic acid water of  claim 7 , wherein said water maintains 80% of said free chlorine after a storage period of 3 months at room temperature.

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