US2014142416A1PendingUtilityA1

System and method for diagnosing a fluid status of a patient

Assignee: ANDUEZA DAGMARPriority: May 18, 2005Filed: Sep 26, 2013Published: May 22, 2014
Est. expiryMay 18, 2025(expired)· nominal 20-yr term from priority
A61B 5/412A61B 5/021A61B 5/029A61B 5/4878A61B 5/02028A61B 5/369A61B 6/03A61B 5/055A61B 5/7282A61B 5/7225A61B 8/04A61B 5/0044A61B 6/503A61B 5/7278A61B 5/0263A61B 8/065A61B 5/7246
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Claims

Abstract

A system and method for diagnosing a fluid status of a patient includes non-invasively determining a left ventricular pressure of blood within a left ventricle of a heart of the patient. The left ventricular pressure is compared to a predefined pressure value to diagnose the fluid status.

Claims

exact text as granted — not AI-modified
1 . A method of diagnosing a fluid status of a patient, the method comprising:
 non-invasively determining a left ventricular pressure of blood within a left ventricle of a heart of the patient by non-invasively measuring a plurality of cardiac parameters of the patient, including a stroke volume of the left ventricle, a mitral valve area, and a left ventricular diastolic filling time; and   comparing the left ventricular pressure to a predefined pressure value to diagnose the fluid status.   
     
     
         2 - 5 . (canceled) 
     
     
         6 . The method according to  claim 1 , wherein the cardiac parameters are measured using one of an echocardiogram apparatus, a magnetic resonance imaging (MRI) apparatus, and a computer aided tomography (CAT) apparatus. 
     
     
         7 . A method of diagnosing a fluid status of a patient, the method comprising:
 non-invasively determining a left ventricular pressure of blood within a left ventricle of a heart of the patient by non-invasively measuring a plurality of cardiac parameters of the patient, including a stroke volume of the left ventricle, a mitral valve area, and a left ventricular diastolic filling time;   calculating a left ventricular end-diastolic pressure using a formula:   
       
         
           
             
               
                 
                   L 
                    
                   
                       
                   
                    
                   V 
                    
                   
                       
                   
                    
                   E 
                    
                   
                       
                   
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                   D 
                    
                   
                       
                   
                    
                   P 
                 
                 = 
                 
                   36 
                    
                   
                     
                       ρ 
                        
                       
                         ( 
                         
                           
                             S 
                              
                             
                                 
                             
                              
                             V 
                           
                           
                             
                               A 
                               mitral 
                             
                              
                             
                               ( 
                               
                                 Δ 
                                  
                                 
                                     
                                 
                                  
                                 
                                   t 
                                   D 
                                 
                               
                               ) 
                             
                           
                         
                         ) 
                       
                     
                     2 
                   
                 
               
               , 
             
           
         
         where LVEDP is the left ventricular end-diastolic pressure, ρ is a density of blood; SV is the stroke volume, A mitral  is the mitral valve area, and Δt D  is the left ventricular diastolic filling time; and 
         comparing the left ventricular pressure to a predefined pressure value to diagnose the fluid status. 
       
     
     
         8 . A method of diagnosing a fluid status of a patient, the method comprising:
 non-invasively determining a left ventricular pressure of blood within a left ventricle of a heart of the patient by non-invasively measuring a plurality of cardiac parameters of the patient, including a stroke volume of the left ventricle, a mitral valve area, a maximum velocity of blood entering the left ventricle, and a left ventricular diastolic filling time;   calculating a left ventricular end-diastolic pressure using a formula:   
       
         
           
             
               
                 
                   L 
                    
                   
                       
                   
                    
                   V 
                    
                   
                       
                   
                    
                   E 
                    
                   
                       
                   
                    
                   D 
                    
                   
                       
                   
                    
                   P 
                 
                 = 
                 
                   
                     3 
                      
                     
                       πρ 
                        
                       
                         ( 
                         
                           S 
                            
                           
                               
                           
                            
                           V 
                         
                         ) 
                       
                     
                      
                     
                       v 
                       max 
                     
                   
                   
                     
                       A 
                       mitral 
                     
                      
                     Δ 
                      
                     
                         
                     
                      
                     
                       t 
                       D 
                     
                   
                 
               
               , 
             
           
         
         where LVEDP is the left ventricular end-diastolic pressure, ρ is a density of blood; SV is the stroke volume, v max  is the maximum velocity of blood, A mitral  is the mitral valve area, and Δt D  is the left ventricular diastolic filling time; and 
         comparing the left ventricular pressure to a predefined pressure value to diagnose the fluid status. 
       
     
     
         9 . A method of diagnosing a fluid status of a patient, the method comprising:
 non-invasively determining a left ventricular pressure of blood within a left ventricle of a heart of the patient by non-invasively measuring a plurality of cardiac parameters, including a volume of the left ventricle, a velocity of blood entering the left ventricle, and a mitral valve area;   monitoring a change in velocity of the blood entering the left ventricle over time;   calculating the left ventricular pressure using a formula:   
       
         
           
             
               
                 
                   L 
                    
                   
                       
                   
                    
                   V 
                    
                   
                       
                   
                    
                   P 
                 
                 = 
                 
                   
                     
                       
                         ρ 
                          
                         
                             
                         
                          
                         V 
                       
                       
                         A 
                         mitral 
                       
                     
                      
                     
                       
                          
                         v 
                       
                       
                          
                         t 
                       
                     
                   
                   + 
                   
                     ρ 
                      
                     
                         
                     
                      
                     
                       v 
                       2 
                     
                   
                 
               
               , 
             
           
         
         where LVP is the left ventricular pressure, ρ is a density of blood; V is the volume of the left ventricle, A mitral  is the mitral valve area, v is the velocity of blood entering the left ventricle, and 
       
       
         
           
             
               
                  
                 v 
               
               
                  
                 t 
               
             
           
         
       
       is the change in velocity over time; and
 comparing the left ventricular pressure to a predefined pressure value to diagnose the fluid status. 
 
     
     
         10 - 17 . (canceled)

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